Expression of matrix metalloproteinases-2, -9 and reversion-inducing cysteine-rich protein with Kazal motifs in gingiva in periodontal health and disease.
Sign Up to like & getrecommendations! Published in 2017 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2016.12.009
Abstract: BACKGROUND AND OBJECTIVE Periodontitis is characterized by pathological destruction of extracellular matrix (ECM) of periodontal tissues. Matrix metalloproteinases (MMPs) promote the occurrence and development of periodontitis by degrading almost all proteins of ECM. RECK (reversion-inducing-cysteine-rich… read more here.
Keywords: protein; expression; reck; mmp mmp ... See more keywords
A molecular mechanism for Wnt ligand-specific signaling
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DOI: 10.1126/science.aat1178
Abstract: How Wnt ligands achieve specificity Wnt signaling is essential for development, tissue homeostasis, and disease. The 19 members of the Wnt family interact promiscuously with the 10 Frizzled receptors, raising the question of how ligand-specific… read more here.
Keywords: wnt; wnt ligand; wnt7; gpr124 ... See more keywords
Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders
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DOI: 10.1126/science.abm4459
Abstract: The blood-brain barrier (BBB) protects the central nervous system (CNS) from harmful blood-borne factors. Although BBB dysfunction is a hallmark of several neurological disorders, therapies to restore BBB function are lacking. An attractive strategy is… read more here.
Keywords: reck; bbb; gpr124 reck; wnt ligands ... See more keywords
The RECK tumor-suppressor protein binds and stabilizes ADAMTS10
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DOI: 10.1242/bio.033985
Abstract: ABSTRACT The tumor suppressor protein RECK has been implicated in the regulation of matrix metalloproteinases (MMPs), NOTCH-signaling and WNT7-signaling. It remains unclear, however, how broad the spectrum of RECK targets extends. To find novel RECK… read more here.
Keywords: tumor suppressor; reck; suppressor protein;
MicroRNA-221 promotes papillary thyroid carcinoma cell migration and invasion via targeting RECK and regulating epithelial–mesenchymal transition
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DOI: 10.2147/ott.s190364
Abstract: Aim The aim of this study was to detect the effects and potential mechanisms of microRNA-221 on a series of biological behaviors of papillary thyroid carcinoma (PTC) cells in vitro and in vivo. Methods First,… read more here.
Keywords: mir 221; expression; invasion; ptc ... See more keywords
MicroRNA-96 Promotes Tumor Invasion in Colorectal Cancer via RECK.
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DOI: 10.21873/anticanres.12442
Abstract: BACKGROUND miR-96 is reported to inhibit reversion cysteine-rich Kazal motif (RECK), which is associated with tumor invasion, in solid cancer types (e.g. breast cancer, non-small cell lung cancer, esophageal cancer). The purpose of this study… read more here.
Keywords: invasion; mir; colorectal cancer; tumor invasion ... See more keywords
Transient Expression of Reck Under Hepatic Ischemia/Reperfusion Conditions Is Associated with Mapk Signaling Pathways
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DOI: 10.3390/biom10050747
Abstract: In this study, we demonstrated the involvement of matrix metalloproteinases (MMPs) in hepatic ischemia/reperfusion (I/R) injury. Our aim is to evaluate the impact of reperfusion on I/R-related changes in RECK, an MMP modulator, and mitogen-activated… read more here.
Keywords: reperfusion; ischemia reperfusion; reck; min reperfusion ... See more keywords