SARS-CoV-2 and other human coronaviruses: Mapping of protease recognition sites, antigenic variation of spike protein and their grouping through molecular phylogenetics
Sign Up to like & getrecommendations! Published in 2021 at "Infection, Genetics and Evolution"
DOI: 10.1016/j.meegid.2021.104729
Abstract: In recent years, a total of seven human pathogenic coronaviruses (HCoVs) strains were identified, i.e., SARS-CoV, SARS-CoV-2, MERS-CoV, HCoV-OC43, HCoV-229E, HCoV-NL63, and HCoV-HKU1. Here, we performed an analysis of the protease recognition sites and antigenic… read more here.
Keywords: recognition sites; recognition; hcov; sars cov ... See more keywords
Recognition Sites for Cancer-Targeting Durg Delivery Systems.
Sign Up to like & getrecommendations! Published in 2019 at "Current drug metabolism"
DOI: 10.2174/1389200220666191003161114
Abstract: BACKGROUND Target-homing drug delivery systems are now gaining significant traction for use as novel therapeutic approaches in antitumor targeting for cancer therapy. Numerous targeted drug delivery systems have been designed to improve the targeting effects… read more here.
Keywords: drug delivery; delivery; delivery systems; recognition sites ... See more keywords
Mapping of Recognition Sites of Monoclonal Antibodies Responsible for the Inhibition of Pneumolysin Functional Activity
Sign Up to like & getrecommendations! Published in 2020 at "Biomolecules"
DOI: 10.3390/biom10071009
Abstract: The pathogenicity of many bacteria, including Streptococcus pneumoniae, depends on pore-forming toxins (PFTs) that cause host cell lysis by forming large pores in cholesterol-containing cell membranes. Therefore, PFTs-neutralising antibodies may provide useful tools for reducing… read more here.
Keywords: ply; monoclonal antibodies; mapping recognition; recognition sites ... See more keywords
Recognition Site Modifiable Macrocycle: Synthesis, Functional Group Variation and Structural Inspection
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28031338
Abstract: Traditional macrocyclic molecules encode recognition sites in their structural backbones, which limits the variation of the recognition sites and thus, would restrict the adjustment of recognition properties. Here, we report a new oligoamide-based macrocycle capable… read more here.
Keywords: recognition; functional groups; variation; synthesis ... See more keywords