In vivo and in vitro inhibition of SCLC by combining dual cancer-specific recombinant adenovirus with Etoposide
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-021-03899-7
Abstract: Oncolytic virotherapy is emerging as an important modality in cancer treatment. In a previous study, we designed and constructed Ad-Apoptin-hTERTp-E1a (Ad-VT), a dual cancer-selective anti-tumor recombinant adenovirus. To explore the therapeutic effect of recombinant adenovirus… read more here.
Keywords: recombinant adenovirus; nci h446; tumor; cancer ... See more keywords
Construction, expression and antiviral activity analysis of recombinant adenovirus expressing human IFITM3 in vitro
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Biological Macromolecules"
DOI: 10.1016/j.ijbiomac.2019.03.161
Abstract: Abstract Interferon-inducible transmembrane protein 3 (IFITM3) inhibits the replication of multiple pathogenic viruses by blocking their entry. In this study, we constructed a shuttle plasmid, harboring human IFITM3. Thereafter, recombinant adenovirus rAd5-IFITM3 was obtained by… read more here.
Keywords: recombinant adenovirus; infection; human ifitm3; rad5 ifitm3 ... See more keywords
Vaccination with recombinant adenovirus expressing multi-stage antigens of Toxoplasma gondii by the mucosal route induces higher systemic cellular and local mucosal immune responses than with other vaccination routes
Sign Up to like & getrecommendations! Published in 2017 at "Parasite"
DOI: 10.1051/parasite/2017013
Abstract: Toxoplasmosis caused by Toxoplasma gondii, an obligate intracellular protozoan, is a cause of congenital disease and abortion in humans and animals. Various vaccination strategies against toxoplasmosis in rodent models have been used in the past… read more here.
Keywords: multi stage; recombinant adenovirus; immune responses; mucosal ... See more keywords
Immunotherapeutic effects of recombinant adenovirus encoding interleukin 12 in experimental pulmonary tuberculosis
Sign Up to like & getrecommendations! Published in 2019 at "Scandinavian Journal of Immunology"
DOI: 10.1111/sji.12743
Abstract: High dose of Mycobacterium tuberculosis (Mtb) strain H37Rv administered by intratracheal injection in BALB/c mice induce progressive tuberculosis (TB). In this model, during the first month there is a temporal control of bacillary growth, in… read more here.
Keywords: immunotherapeutic effects; adenovirus encoding; recombinant adenovirus; tuberculosis ... See more keywords
Recombinant Adenovirus siRNA Knocking Down the Ndufs4 Gene Alleviates Myocardial Apoptosis Induced by Oxidative Stress Injury
Sign Up to like & getrecommendations! Published in 2023 at "Cardiology Research and Practice"
DOI: 10.1155/2023/8141129
Abstract: Oxidative stress results in myocardial cell apoptosis and even life-threatening heart failure in myocardial ischemia-reperfusion injury. Specific blocking of the complex I could reduce cell apoptosis. Ndufs4 is a nuclear-encoded subunit of the mitochondrial complex… read more here.
Keywords: apoptosis; ndufs4 gene; recombinant adenovirus; oxidative stress ... See more keywords
Vaccination with recombinant adenovirus expressing peste des petits ruminants virus-F or -H proteins elicits T cell responses to epitopes that arises during PPRV infection
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary Research"
DOI: 10.1186/s13567-017-0482-x
Abstract: Peste des petits ruminants virus (PPRV) causes an economically important disease that limits productivity in small domestic ruminants and often affects the livestock of the poorest populations in developing countries. Animals that survive PPRV develop… read more here.
Keywords: recombinant adenovirus; des petits; vaccination; cell ... See more keywords
Immunogenicity of the recombinant adenovirus fusion-expressing E0-E2 gene of the classical swine fever virus
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.1054651
Abstract: Adenovirus vector vaccines have been the mainstream research direction of CSF vaccines, due to the replication deficiency of adenovirus vectors, achieving double effects with the safety of inactivated vaccines and the efficacy of live vaccines.… read more here.
Keywords: immunization; recombinant adenovirus; dose; csfv ... See more keywords
Clinical and Immunologic Efficacy of the Recombinant Adenovirus Type-5-Vectored (CanSino Bio) Vaccine in University Professors during the COVID-19 Delta Wave
Sign Up to like & getrecommendations! Published in 2022 at "Vaccines"
DOI: 10.3390/vaccines10050656
Abstract: Information regarding the efficacy of the recombinant adenovirus type-5-vectored (CanSino Bio) vaccine against the COVID-19 disease in a real-life setting is limited. A retrospective cohort study was carried out in the teaching university community of… read more here.
Keywords: recombinant adenovirus; adenovirus type; cansino; cansino bio ... See more keywords