Guiding recombinant antivenom development by omics technologies.
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DOI: 10.1016/j.nbt.2017.05.005
Abstract: In this review, the different approaches that have been employed with the aim of developing novel antivenoms against animal envenomings are presented and discussed. Reported efforts have focused on the use of innovative immunization strategies,… read more here.
Keywords: omics technologies; recombinant antivenom; antivenom development; guiding recombinant ... See more keywords
Pros and cons of different therapeutic antibody formats for recombinant antivenom development
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DOI: 10.1016/j.toxicon.2018.03.004
Abstract: &NA; Antibody technologies are being increasingly applied in the field of toxinology. Fuelled by the many advances in immunology, synthetic biology, and antibody research, different approaches and antibody formats are being investigated for the ability… read more here.
Keywords: recombinant antivenom; antivenom development; antibody; antibody formats ... See more keywords
Nanobody-based recombinant antivenom for cobra, mamba and rinkhals bites
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DOI: 10.1038/s41586-025-09661-0
Abstract: Each year, snakebite envenoming claims thousands of lives and causes severe injury to victims across sub-Saharan Africa, many of whom depend on antivenoms derived from animal plasma as their sole treatment option1. Traditional antivenoms are… read more here.
Keywords: venom induced; nanobody based; based recombinant; antivenom ... See more keywords