A semi-interpenetrating network of polyacrylamide and recombinant basement membrane allows pluripotent cell culture in a soft, ligand-rich microenvironment.
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DOI: 10.1016/j.biomaterials.2016.12.005
Abstract: The physical properties of the extracellular matrix play an essential role in guiding stem cell differentiation and tissue morphogenesis both in vivo and in vitro. Existing work to investigate the role of matrix mechanics in directing stem… read more here.
Keywords: pluripotent; basement membrane; polyacrylamide recombinant; recombinant basement ... See more keywords