Enhancing recovery of recombinant hepatitis B surface antigen in lab-scale and large-scale anion-exchange chromatography by optimizing the conductivity of buffers.
Sign Up to like & getrecommendations! Published in 2018 at "Protein expression and purification"
DOI: 10.1016/j.pep.2017.08.011
Abstract: In biopharmaceutical science, ion-exchange chromatography (IEC) is a well-known purification technique to separate the impurities such as host cell proteins from recombinant proteins. However, IEC is one of the limiting steps in the purification process… read more here.
Keywords: recovery; recombinant hepatitis; conductivity; exchange ... See more keywords
Evaluating the Immunological Properties of Recombinant Hepatitis B Surface Antigen Using a Multitiered In Vivo and In Vitro Approach.
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DOI: 10.1177/08828245251389235
Abstract: The immunological properties of recombinant hepatitis B surface antigen (rHBsAg), prepared using yeast (Saccharomyces cerevisiae [SC]) and Chinese hamster ovary (CHO) cells, were evaluated through in vitro and in vivo assays to support the efficacy… read more here.
Keywords: rhbsag; rhbsag cho; recombinant hepatitis; immunological properties ... See more keywords
Development of a Monocyte Activation Test for Evaluating Recombinant Hepatitis B Vaccine: A Novel Approach for Pyrogen Assessment
Sign Up to like & getrecommendations! Published in 2024 at "Iranian Biomedical Journal"
DOI: 10.61186/ibj.4100
Abstract: Background: Injectable products, particularly human vaccines, must be free from fever-inducing agents and thoroughly tested for pyrogens as part of a quality control. Consequently, manufacturing facilities are required to conduct appropriate pyrogen tests per pharmacopoeial… read more here.
Keywords: recombinant hepatitis; hepatitis vaccine; development monocyte; vaccine ... See more keywords
Protectivity and safety following recombinant hepatitis B vaccine with different source of bulk compared to hepatitis B (Bio Farma) vaccine in Indonesia
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Vaccine Research"
DOI: 10.7774/cevr.2022.11.1.43
Abstract: Purpose Indonesia, a high populous and the second-highest country in epidemicity of hepatitis B in South-East Asia require maintaining its capacity of monovalent hepatitis B production to keep up with both the national immunization program… read more here.
Keywords: hepatitis vaccine; bio farma; hepatitis; vaccine ... See more keywords