Efficient coexpression of recombinant human fusion collagen with prolyl 4‐hydroxylase from Bacillus anthracis in Escherichia coli
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.2396
Abstract: Collagen family members, the most abundant proteins in the human body, are widely used in biomedical fields and tissue engineering industries. However, the applications of collagen remain mostly relying on material derived from native tissues… read more here.
Keywords: human fusion; fusion collagen; prolyl; collagen ... See more keywords
Spectroscopic analysis of recombinant human growth hormone in presence of sucrose and trehalose.
Sign Up to like & getrecommendations! Published in 2023 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2452
Abstract: Recombinant human growth. This article is protected by copyright. All rights reserved. read more here.
Keywords: analysis recombinant; spectroscopic analysis; recombinant human; growth hormone ... See more keywords
Blockage of undesirable endocytosis of recombinant human growth/differentiation factor‐5 in Chinese hamster ovary cell cultures requires heparin analogs with specific chain lengths
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology Journal"
DOI: 10.1002/biot.202100227
Abstract: Cell surface heparan sulfate proteoglycan (HSPG)‐mediated endocytosis lowers the yield of recombinant human bone morphogenetic proteins (rhBMPs), such as rhBMP‐2 and rhBMP‐4, from Chinese hamster ovary (CHO) cell cultures. Exogenous recombinant human growth/differentiation factor‐5 (rhGDF‐5),… read more here.
Keywords: chain; recombinant human; rhgdf internalization; cell cultures ... See more keywords
A simplified method for the efficient purification and refolding of recombinant human TRAIL
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology Progress"
DOI: 10.1002/btpr.3007
Abstract: Tumor necrosis factor (TNF)‐related apoptosis‐inducing ligand (TRAIL) belongs to the TNF cytokine superfamily that specifically induces apoptosis in a broad spectrum of human cancer cell lines but not in most healthy cells. The antitumor potential… read more here.
Keywords: recombinant human; efficient purification; trail; human trail ... See more keywords
Efficacy and safety of recombinant human lymphotoxin‐α derivative with cisplatin and fluorouracil in patients with metastatic esophageal squamous cell carcinoma: A randomized, multicenter, open‐label, controlled, phase 2b trial
Sign Up to like & getrecommendations! Published in 2017 at "Cancer"
DOI: 10.1002/cncr.30845
Abstract: Recombinant human lymphotoxin‐α derivative (rhLTα‐Da) is a lymphotoxin‐α derivative that is missing 27 N‐terminal amino acid residues. Previous studies indicated a benefit from the addition of rhLTα‐Da to cisplatin‐based treatment in patients with metastatic esophageal… read more here.
Keywords: recombinant human; lymphotoxin; metastatic esophageal; patients metastatic ... See more keywords
Pharmacokinetics and Pharmacodynamics of Two Formulations of Pegylated Recombinant Human Granulocyte Colony‐Stimulating Factor in Healthy Chinese Subjects: An Open‐Label, Randomized, Parallel‐Design Bioavailability Study
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.819
Abstract: Pegylated recombinant human granulocyte colony‐stimulating factor (PEG‐rhG‐CSF, pegfilgrastim) is a long‐acting derivative of recombinant human granulocyte colony‐stimulating factor with limited renal clearance and a longer half‐life. It is used for the prevention of febrile neutropenia,… read more here.
Keywords: recombinant human; treatment; peg rhg; rhg csf ... See more keywords
The Use of RNA-Based 5'-Aminolevulinate Synthase 2 Biomarkers in Dried Blood Spots to Detect Recombinant Human Erythropoietin Micro-Doses.
Sign Up to like & getrecommendations! Published in 2021 at "Drug testing and analysis"
DOI: 10.1002/dta.3123
Abstract: The hematological module of the Athlete Biological Passport (ABP) is used for indirect detection of blood manipulations; however, the use of this method to detect doping, such as with micro-doses of recombinant human erythropoietin (rhEPO),… read more here.
Keywords: recombinant human; rhepo micro; micro dosing; micro ... See more keywords
Recombinant human brain natriuretic peptide ameliorates venous return function in congestive heart failure
Sign Up to like & getrecommendations! Published in 2022 at "ESC Heart Failure"
DOI: 10.1002/ehf2.13987
Abstract: Recombinant human brain natriuretic peptide (rh‐BNP) is commonly used as a decongestive therapy. This study aimed to investigate the instant effects of rh‐BNP on cardiac output and venous return function in post‐cardiotomy patients with congestive… read more here.
Keywords: heart failure; brain natriuretic; recombinant human; human brain ... See more keywords
Intermediate purification of CHO‐derived recombinant human Factor IX using hydrophobic interaction membrane‐based chromatography and its comparison to a sulfated resin
Sign Up to like & getrecommendations! Published in 2017 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201700226
Abstract: This work investigated the use of hydrophobic interaction membrane chromatography for intermediate purification of recombinant human Factor IX (rFIX) produced by CHO cells. The first purification step was based on a strong anion exchange monolith,… read more here.
Keywords: hydrophobic interaction; recombinant human; factor; intermediate purification ... See more keywords
Characterization and high‐yield production of non‐N‐glycosylated recombinant human BCMA‐Fc in Pichia pastoris
Sign Up to like & getrecommendations! Published in 2017 at "Engineering in Life Sciences"
DOI: 10.1002/elsc.201600039
Abstract: B‐cell maturation antigen (BCMA) fused at the C‐terminus to the Fc portion of human IgG1 (BCMA‐Fc) blocks B‐cell activating factor (BAFF) and proliferation‐inducing ligand (APRIL)‐mediated B‐cell activation, leading to immune disorders. The fusion protein has… read more here.
Keywords: recombinant human; production; bcma; human bcma ... See more keywords
Recombinant human growth hormone treatment of mice suppresses inflammation and apoptosis caused by skin flap ischemia–reperfusion injury
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29122
Abstract: This study was to investigate the effects of recombinant human growth hormone (rhGh) on ischemia‐reperfusion (I/R) injury of mouse flaps. read more here.
Keywords: recombinant human; human growth; growth hormone; ischemia reperfusion ... See more keywords