Sequential pulmonary immunization with heterologous recombinant influenza A virus tuberculosis vaccines protects against murine M. tuberculosis infection.
Sign Up to like & getrecommendations! Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2018.03.037
Abstract: Tuberculosis (TB) infection affects a quarter of the global population resulting in a large burden of TB disease and mortality. The long-term control of TB requires vaccines with greater efficacy and durability than the current… read more here.
Keywords: immunization; recombinant influenza; pulmonary immunization; tuberculosis ... See more keywords
Generation of recombinant influenza virus bearing strep tagged PB2 and effective identification of interactional host factors.
Sign Up to like & getrecommendations! Published in 2021 at "Veterinary microbiology"
DOI: 10.1016/j.vetmic.2021.108985
Abstract: The genome of influenza A virus is negative-sense and segmented RNA, which is transcribed and replicated by the viral RNA-dependent RNA polymerase (RdRp) during the virus life cycle. The viral RdRp is thought to be… read more here.
Keywords: host factors; recombinant influenza; strep tagged; host ... See more keywords
Cross protection by inactivated recombinant influenza viruses containing chimeric hemagglutinin conjugates with a conserved neuraminidase or M2 ectodomain epitope.
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DOI: 10.1016/j.virol.2020.08.003
Abstract: Influenza virus neuraminidase (NA) contains a universally conserved epitope (NAe, NA222-230). However, no studies have reported vaccines targeting this NA conserved epitope and inducing antibodies recognizing NAe. The extracellular domain of M2 (M2e) is considered… read more here.
Keywords: m2e; inactivated recombinant; recombinant influenza; epitope ... See more keywords
Engineered Nanoparticle Applications for Recombinant Influenza Vaccines.
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DOI: 10.1021/acs.molpharmaceut.0c00383
Abstract: Influenza viruses cause seasonal epidemics and represent a pandemic risk. With current vaccines methods struggling to protect populations against emerging strains, there is demand for a next-generation flu vaccine capable of providing broad protection. Recombinant… read more here.
Keywords: influenza vaccines; nanoparticle; engineered nanoparticle; recombinant influenza ... See more keywords
Safety and Immunogenicity of a Recombinant Influenza Vaccine: A Randomized Trial
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DOI: 10.1542/peds.2017-3021
Abstract: Recombinant HA provided better protection than the inactivated influenza vaccine in adults ≥50 years old but lower immunogenicity in children read more here.
Keywords: immunogenicity; influenza vaccine; safety immunogenicity; recombinant influenza ... See more keywords
Recent Progress in Recombinant Influenza Vaccine Development Toward Heterosubtypic Immune Response
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.878943
Abstract: Flu, a viral infection caused by the influenza virus, is still a global public health concern with potential to cause seasonal epidemics and pandemics. Vaccination is considered the most effective protective strategy against the infection.… read more here.
Keywords: heterosubtypic; recombinant influenza; development; immune response ... See more keywords
High-Yield Expression and Purification of Recombinant Influenza Virus Proteins from Stably-Transfected Mammalian Cell Lines
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DOI: 10.3390/vaccines8030462
Abstract: Influenza viruses infect millions of people each year, resulting in significant morbidity and mortality in the human population. Therefore, generation of a universal influenza virus vaccine is an urgent need and would greatly benefit public… read more here.
Keywords: influenza virus; recombinant influenza; cell lines;