Intracranial Bleeding as a Major Problem Among Neonates With Disseminated Intravascular Coagulation After the Introduction of Recombinant Thrombomodulin
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000002441
Abstract: A standard treatment for disseminated intravascular coagulation in neonates has not yet been established. We analyzed the outcomes of 23 neonates who developed disseminated intravascular coagulation due to infection or asphyxia between 2004 and 2017.… read more here.
Keywords: intravascular coagulation; recombinant thrombomodulin; major problem; disseminated intravascular ... See more keywords
Thrombomodulin in disseminated intravascular coagulation and other critical conditions—a multi-faceted anticoagulant protein with therapeutic potential
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DOI: 10.1186/s13054-019-2552-0
Abstract: Thrombomodulin plays a vital role in maintaining intravascular patency due to its anticoagulant, antiinflammatory, and cytoprotective properties. However, under pathological conditions such as sepsis and systemic inflammation, endothelial thrombomodulin expression is downregulated and its function… read more here.
Keywords: coagulation critical; thrombomodulin disseminated; disseminated intravascular; intravascular coagulation ... See more keywords
TAFRO Syndrome with Disseminated Intravascular Coagulation Successfully Treated with Tocilizumab and Recombinant Thrombomodulin
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DOI: 10.2169/internalmedicine.9484-17
Abstract: TAFRO syndrome is a systemic inflammatory disorder that is characterized by thrombocytopenia, anasarca, myelofibrosis, renal dysfunction, and organomegaly. Although thrombocytopenia is one of the major features of TAFRO syndrome, complications of disseminated intravascular coagulation (DIC)… read more here.
Keywords: disseminated intravascular; intravascular coagulation; successfully treated; recombinant thrombomodulin ... See more keywords