Articles with "recombination hotspot" as a keyword



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Deep learning identifies and quantifies recombination hotspot determinants

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Published in 2022 at "Bioinformatics"

DOI: 10.1093/bioinformatics/btac234

Abstract: MOTIVATION Recombination is one of the essential genetic processes for sexually reproducing organisms, which can happen more frequently in some regions, called recombination hotspots. Although several factors, such as PRDM9 binding motifs, are known to… read more here.

Keywords: identifies quantifies; recombination hotspot; hotspot; learning identifies ... See more keywords
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Regulation Mechanisms of Meiotic Recombination Revealed from the Analysis of a Fission Yeast Recombination Hotspot ade6-M26

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Published in 2022 at "Biomolecules"

DOI: 10.3390/biom12121761

Abstract: Meiotic recombination is a pivotal event that ensures faithful chromosome segregation and creates genetic diversity in gametes. Meiotic recombination is initiated by programmed double-strand breaks (DSBs), which are catalyzed by the conserved Spo11 protein. Spo11… read more here.

Keywords: recombination hotspot; recombination; ade6 m26; meiotic recombination ... See more keywords