Determinants of the recommended phase 2 dose of molecular targeted agents
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DOI: 10.1002/cncr.30579
Abstract: The recommended phase 2 dose (RP2D) of anticancer agents is determined traditionally by dose‐limiting toxicities. Nontoxicity or biological endpoints such as pharmacokinetics, pharmacodynamics, and efficacy can also be used to identify RP2D, which may be… read more here.
Keywords: targeted agents; phase dose; determinants recommended; recommended phase ... See more keywords