Articles with "reconsolidation" as a keyword



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Modulation of naturalistic maladaptive memories using behavioural and pharmacological reconsolidation-interfering strategies: a systematic review and meta-analysis of clinical and ‘sub-clinical’ studies

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Published in 2018 at "Psychopharmacology"

DOI: 10.1007/s00213-018-4983-8

Abstract: BackgroundConsolidated memories can undergo enduring modification through retrieval-dependent treatments that modulate reconsolidation. This represents a potentially transformative strategy for weakening or overwriting the maladaptive memories that underlie substance use and anxiety/trauma-related disorders. However, modulation of… read more here.

Keywords: substance use; maladaptive memories; meta; reconsolidation ... See more keywords
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Reconsolidation of human motor memory: From boundary conditions to behavioral interventions—How far are we from clinical applications?

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Published in 2018 at "Behavioural Brain Research"

DOI: 10.1016/j.bbr.2018.07.003

Abstract: The memory reconsolidation hypothesis states that a previously consolidated and stable memory can return to a temporary labile state after retrieved, requiring a new stabilization process. During the labile period, the memory trace is vulnerable… read more here.

Keywords: motor memory; boundary conditions; human motor; reconsolidation ... See more keywords
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The metaplastic effects of ketamine on sucrose renewal and contextual memory reconsolidation in rats

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Published in 2020 at "Behavioural Brain Research"

DOI: 10.1016/j.bbr.2019.112347

Abstract: Metaplastic effects of the NMDARs blocker ketamine at the neural and behavioural levels have been described as potential mechanisms underlying the beneficial effects in treatment-resistant depression. However, ketamine effects on addictive behaviours are still unexplored.… read more here.

Keywords: memory reconsolidation; renewal; metaplastic effects; reconsolidation ... See more keywords
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Memory reconsolidation impairments in sign-tracking to an audiovisual compound stimulus

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Published in 2020 at "Behavioural Brain Research"

DOI: 10.1016/j.bbr.2020.112774

Abstract: Studies of memory reconsolidation of pavlovian memories have typically employed unimodal conditioned stimuli, despite the use of multimodal compound stimuli in other settings. Here we studied sign-tracking behaviour to a compound audiovisual stimulus. First, we… read more here.

Keywords: sign tracking; audiovisual compound; compound stimulus; compound ... See more keywords
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Extinction during reconsolidation eliminates recovery of fear conditioned to fear-irrelevant and fear-relevant stimuli.

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Published in 2017 at "Behaviour research and therapy"

DOI: 10.1016/j.brat.2017.01.017

Abstract: Extant literature suggests that extinction training delivered during the memory reconsolidation period is superior to traditional extinction training in the reduction of fear recovery, as it targets the original fear memory trace. At present it… read more here.

Keywords: recovery; fear relevant; fear; extinction ... See more keywords
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A novel method to trigger the reconsolidation of fear memory.

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Published in 2019 at "Behaviour research and therapy"

DOI: 10.1016/j.brat.2019.103461

Abstract: The procedure of memory reconsolidation provides an opportunity to improve some mental disorders caused by maladaptive memories, such as Posttraumatic Stress Disorder. Prediction error was considered a necessary condition for triggering memory reconsolidation. However, it… read more here.

Keywords: prediction error; memory; reconsolidation; memory reconsolidation ... See more keywords
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Nitrous oxide may interfere with the reconsolidation of drinking memories in hazardous drinkers in a prediction-error-dependent manner

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Published in 2018 at "European Neuropsychopharmacology"

DOI: 10.1016/j.euroneuro.2018.05.001

Abstract: Weakening drinking-related reward memories by blocking their reconsolidation is a potential novel strategy for treating alcohol use disorders. However, few viable pharmacological options exist for reconsolidation interference in humans. We therefore examined whether the NMDA… read more here.

Keywords: prediction error; retrieval; nitrous oxide; alcohol ... See more keywords
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Neutral mood induction during reconsolidation reduces accuracy, but not vividness and anxiety of emotional episodic memories.

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Published in 2017 at "Journal of behavior therapy and experimental psychiatry"

DOI: 10.1016/j.jbtep.2016.05.001

Abstract: BACKGROUND AND OBJECTIVES Consolidated memories become labile upon reactivation and as a result have to go through reconsolidation to become re-stabilized. This property of memory may potentially be used to reduce the impact of highly… read more here.

Keywords: episodic memories; accuracy; accuracy vividness; vividness anxiety ... See more keywords
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Cathodal transcranial direct current stimulation on the prefrontal cortex applied after reactivation attenuates fear memories and prevent reinstatement after extinction.

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Published in 2021 at "Journal of psychiatric research"

DOI: 10.1016/j.jpsychires.2021.12.025

Abstract: BACKGROUND In the last decade, pharmacological strategies targeting reconsolidation after memory retrieval have shown promising efforts to attenuate persistent memories and overcome fear recovery. However, most reconsolidation inhibiting agents have not been approved for human… read more here.

Keywords: fear memories; reactivation; cathodal; extinction ... See more keywords
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GABAergic neurons in the insular cortex play an important role in cue-morphine reward memory reconsolidation.

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Published in 2020 at "Life sciences"

DOI: 10.1016/j.lfs.2020.117655

Abstract: AIMS There have been recent reports that reconsolidation-based interventions attenuate drug reward memories in rodents. The insular cortex (IC) is an essential part of neural circuits that underlie cue-drug memory reconsolidation. GABAergic interneurons in the… read more here.

Keywords: memory reconsolidation; insular cortex; reconsolidation; reward ... See more keywords
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Blockade of muscarinic receptors impairs reconsolidation of older fear memory by decreasing cholinergic neurotransmission: A study in rat model of PTSD.

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Published in 2020 at "Life sciences"

DOI: 10.1016/j.lfs.2020.118014

Abstract: The age and strength of fear memory are two potential parameters that can be influenced by the impairing effects of pharmacological agents on reconsolidation of fear memory. In reconsolidation, stored information is rendered labile again… read more here.

Keywords: reconsolidation; memory; model ptsd; fear memory ... See more keywords