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Published in 2018 at "Psychopharmacology"
DOI: 10.1007/s00213-018-4983-8
Abstract: BackgroundConsolidated memories can undergo enduring modification through retrieval-dependent treatments that modulate reconsolidation. This represents a potentially transformative strategy for weakening or overwriting the maladaptive memories that underlie substance use and anxiety/trauma-related disorders. However, modulation of…
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Keywords:
substance use;
maladaptive memories;
meta;
reconsolidation ... See more keywords
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Published in 2018 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2018.07.003
Abstract: The memory reconsolidation hypothesis states that a previously consolidated and stable memory can return to a temporary labile state after retrieved, requiring a new stabilization process. During the labile period, the memory trace is vulnerable…
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Keywords:
motor memory;
boundary conditions;
human motor;
reconsolidation ... See more keywords
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Published in 2020 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2019.112347
Abstract: Metaplastic effects of the NMDARs blocker ketamine at the neural and behavioural levels have been described as potential mechanisms underlying the beneficial effects in treatment-resistant depression. However, ketamine effects on addictive behaviours are still unexplored.…
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Keywords:
memory reconsolidation;
renewal;
metaplastic effects;
reconsolidation ... See more keywords
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Published in 2020 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2020.112774
Abstract: Studies of memory reconsolidation of pavlovian memories have typically employed unimodal conditioned stimuli, despite the use of multimodal compound stimuli in other settings. Here we studied sign-tracking behaviour to a compound audiovisual stimulus. First, we…
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Keywords:
sign tracking;
audiovisual compound;
compound stimulus;
compound ... See more keywords
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Published in 2017 at "Behaviour research and therapy"
DOI: 10.1016/j.brat.2017.01.017
Abstract: Extant literature suggests that extinction training delivered during the memory reconsolidation period is superior to traditional extinction training in the reduction of fear recovery, as it targets the original fear memory trace. At present it…
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Keywords:
recovery;
fear relevant;
fear;
extinction ... See more keywords
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Published in 2019 at "Behaviour research and therapy"
DOI: 10.1016/j.brat.2019.103461
Abstract: The procedure of memory reconsolidation provides an opportunity to improve some mental disorders caused by maladaptive memories, such as Posttraumatic Stress Disorder. Prediction error was considered a necessary condition for triggering memory reconsolidation. However, it…
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Keywords:
prediction error;
memory;
reconsolidation;
memory reconsolidation ... See more keywords
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Published in 2018 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2018.05.001
Abstract: Weakening drinking-related reward memories by blocking their reconsolidation is a potential novel strategy for treating alcohol use disorders. However, few viable pharmacological options exist for reconsolidation interference in humans. We therefore examined whether the NMDA…
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Keywords:
prediction error;
retrieval;
nitrous oxide;
alcohol ... See more keywords
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Published in 2017 at "Journal of behavior therapy and experimental psychiatry"
DOI: 10.1016/j.jbtep.2016.05.001
Abstract: BACKGROUND AND OBJECTIVES Consolidated memories become labile upon reactivation and as a result have to go through reconsolidation to become re-stabilized. This property of memory may potentially be used to reduce the impact of highly…
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Keywords:
episodic memories;
accuracy;
accuracy vividness;
vividness anxiety ... See more keywords
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Published in 2021 at "Journal of psychiatric research"
DOI: 10.1016/j.jpsychires.2021.12.025
Abstract: BACKGROUND In the last decade, pharmacological strategies targeting reconsolidation after memory retrieval have shown promising efforts to attenuate persistent memories and overcome fear recovery. However, most reconsolidation inhibiting agents have not been approved for human…
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Keywords:
fear memories;
reactivation;
cathodal;
extinction ... See more keywords
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Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117655
Abstract: AIMS There have been recent reports that reconsolidation-based interventions attenuate drug reward memories in rodents. The insular cortex (IC) is an essential part of neural circuits that underlie cue-drug memory reconsolidation. GABAergic interneurons in the…
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Keywords:
memory reconsolidation;
insular cortex;
reconsolidation;
reward ... See more keywords
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Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118014
Abstract: The age and strength of fear memory are two potential parameters that can be influenced by the impairing effects of pharmacological agents on reconsolidation of fear memory. In reconsolidation, stored information is rendered labile again…
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Keywords:
reconsolidation;
memory;
model ptsd;
fear memory ... See more keywords