Peripheral blood biomarkers of early immune reconstitution in newly diagnosed multiple myeloma
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Hematology"
DOI: 10.1002/ajh.25365
Abstract: Peripheral blood biomarkers of tumor microenvironment and immune surveillance are independent prognostic factors in multiple myeloma. The timing and prognostic impact of immune reconstitution has been studied after autologous hematopoietic stem cell transplantation, less is… read more here.
Keywords: early immune; newly diagnosed; reconstitution; multiple myeloma ... See more keywords
Cytomegalovirus kinetics after hematopoietic cell transplantation reveal peak titers with differential impact on mortality, relapse and immune reconstitution
Sign Up to like & getrecommendations! Published in 2021 at "American Journal of Hematology"
DOI: 10.1002/ajh.26094
Abstract: Even in the era of PCR‐based monitoring, prophylaxis, and preemptive therapy, Cytomegalovirus (CMV) viremia remains a relevant cause of non‐relapse mortality (NRM) after allogeneic hematopoietic cell transplantation (HCT). However, studies using binary analysis (presence/absence of… read more here.
Keywords: cmv; reconstitution; relapse; peak ... See more keywords
Predicting CD4 T‐Cell Reconstitution Following Pediatric Hematopoietic Stem Cell Transplantation
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.621
Abstract: Hematopoietic stem cell transplantation (HSCT) is an increasingly common treatment for children with a range of hematological disorders. Conditioning with cytotoxic chemotherapy and total body irradiation leaves patients severely immunocompromised. T‐cell reconstitution can take several… read more here.
Keywords: cell reconstitution; reconstitution; stem cell; transplantation ... See more keywords
Bi-exponential modelling of [Formula: see text] reconstitution kinetics in trained cyclists.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of applied physiology"
DOI: 10.1007/s00421-021-04874-3
Abstract: PURPOSE The aim of this study was to investigate the individual [Formula: see text] reconstitution kinetics of trained cyclists following repeated bouts of incremental ramp exercise, and to determine an optimal mathematical model to describe… read more here.
Keywords: see text; recovery; text reconstitution; reconstitution ... See more keywords
Application of Magnetic Resonance to Assess Lyophilized Drug Product Reconstitution
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutical Research"
DOI: 10.1007/s11095-019-2591-x
Abstract: PurposeDynamic in-situ proton (1H) magnetic resonance imaging (MRI) and 1H T2-relaxometry experiments are described in an attempt to: (i) understand the physical processes, that occur during the reconstitution of lyophilized bovine serum albumin (BSA) and… read more here.
Keywords: relaxation data; magnetic resonance; time; reconstitution ... See more keywords
Rapid and Robust CD4+ and CD8+ T-, NK-, B-Cell, Dendritic Cell, and Monocyte Reconstitution after Nicotinamide-Expanded Cord Blood Transplantation
Sign Up to like & getrecommendations! Published in 2019 at "Biology of Blood and Marrow Transplantation"
DOI: 10.1016/j.bbmt.2018.12.133
Abstract: Introduction Nicotinamide-expanded cord blood (NiCord) is a potential alternative source for allogeneic hematopoietic cell transplantation (HCT) when an HLA-id donor is lacking. A phase 1/2 trial with standalone NiCord HCT showed rapid neutrophil- (11 days)… read more here.
Keywords: reconstitution; cd4; transplantation; cell ... See more keywords
Thymic Reconstitution after Damage Is Influenced By Zinc Status
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DOI: 10.1016/j.bbmt.2019.12.403
Abstract: T cell reconstitution, which is dependent on thymus function, is significantly delayed after hematopoietic stem cell transplant; leading to morbidity and mortality due to infection and possibly even malignant relapse. Zinc, the second most abundant… read more here.
Keywords: zinc; reconstitution; damage; zinc supplementation ... See more keywords
Prospective Open-Label Phase II Trial of Individualized Anti-Thymocyte Globulin for Improved T-Cell Reconstitution after Pediatric Allogeneic Hematopoietic Cell Transplantation: The Parachute-Study
Sign Up to like & getrecommendations! Published in 2020 at "Biology of Blood and Marrow Transplantation"
DOI: 10.1016/j.bbmt.2019.12.577
Abstract: Introduction Rabbit anti-thymocyte globulin (ATG) is used in allogeneic hematopoietic cell transplantation (HCT) to prevent graft-versus-host-disease (GvHD) and graft failure (GF). Its main and unpredictable toxicity includes poor immune reconstitution associated with increased relapse, viral… read more here.
Keywords: anti thymocyte; thymocyte globulin; cell reconstitution; reconstitution ... See more keywords
Reconstitution of full-length human caveolin-1 into phospholipid bicelles: Validation by analytical ultracentrifugation.
Sign Up to like & getrecommendations! Published in 2020 at "Biophysical chemistry"
DOI: 10.1016/j.bpc.2020.106339
Abstract: A significant hurdle in obtaining biophysical information on membrane proteins is developing a successful strategy for their reconstitution into a suitable membrane mimic. In particular, utilization of the more 'native-like' membrane mimics such as bicelles… read more here.
Keywords: full length; reconstitution; caveolin; analytical ultracentrifugation ... See more keywords
Surface tension-driven effects in the reconstitution of food powders
Sign Up to like & getrecommendations! Published in 2019 at "Chemical Engineering Research and Design"
DOI: 10.1016/j.cherd.2019.04.015
Abstract: Abstract Quick powder reconstitution is generally necessary for consumer acceptance of dehydrated food materials; thus, an improved understanding of the mechanisms preventing complete reconstitution can help aid the discovery of solutions to improve product quality.… read more here.
Keywords: powder; reconstitution; food; surface tension ... See more keywords
Reactivation of BK virus after double umbilical cord blood transplantation in adults correlates with impaired reconstitution of CD4+ and CD8+ T effector memory cells and increase of T regulatory cells.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical immunology"
DOI: 10.1016/j.clim.2019.06.010
Abstract: BK virus (BKV), a human polyomavirus that remains latent in renal epithelial cells, can be reactivated after hematopoietic stem cell transplantation (HSCT) leading to hemorrhagic cystitis. The incidence of BK viremia is higher after Umbilical… read more here.
Keywords: cd8; cord blood; umbilical cord; reconstitution ... See more keywords