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Published in 2022 at "European journal of immunology"
DOI: 10.1002/eji.202249815
Abstract: The immune reconstitution inflammatory syndrome (IRIS) can be a complication of anti-retroviral therapy (ART) in patients with advanced HIV, but its pathogenesis is uncertain. In tuberculosis (TB) endemic countries, IRIS is often associated with mycobacterial… read more here.
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Published in 2017 at "Hematological Oncology"
DOI: 10.1002/hon.2309
Abstract: Trichosporon has recently emerged as a life‐threatening opportunistic fungal pathogen, notably in patients with hematological malignancy. Fungemia, sometimes associated with cutaneous lesions and/or pneumonitis, is the major clinical form. Here, we report two cases of… read more here.
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Published in 2021 at "Chest"
DOI: 10.1016/j.chest.2021.07.1078
Abstract: TOPIC: Diffuse Lung Disease TYPE: Fellow Case Reports INTRODUCTION: Immune reconstitution inflammatory syndrome (IRIS) has a wide variety of presentations including lung involvement with respiratory failure [1]. While traditionally invoked in AIDS, IRIS is also… read more here.
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Published in 2020 at "IDCases"
DOI: 10.1016/j.idcr.2020.e00699
Abstract: We present a case of Cryptococcus neoformans in an immunocompetent middle-aged woman with a disseminated manifestation of pulmonary cryptoccoma and cryptococcal meningitis resulting in bilateral blindness. The presentation was complicated by delayed diagnosis resulting in… read more here.
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Published in 2017 at "Seminars in diagnostic pathology"
DOI: 10.1053/j.semdp.2017.04.010
Abstract: Antiretroviral therapy has significantly improved the quality and length of life for those patients able to access effective and sustained treatment. The resulting restoration of the immune response is associated with a change in the… read more here.
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Published in 2023 at "Infectious diseases"
DOI: 10.1080/23744235.2023.2208210
Abstract: Abstract Background Mycobacterium haemophilum is a nontuberculous mycobacterium with fastidious in vitro growth requirements and an increasingly reported cause of extrapulmonary disease. Timely diagnosis and management of M. haemophilum infections and the immune reconstitution inflammatory… read more here.
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Published in 2017 at "AIDS research and human retroviruses"
DOI: 10.1089/aid.2017.0030
Abstract: A 10-year review of disseminated Mycobacterium avium complex (MAC) infection and MAC-immune reconstitution inflammatory syndrome in HIV-positive patients (2004-2014) at a state-wide tertiary referral HIV service demonstrates that despite advances in antiretroviral therapy, MAC infection… read more here.
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Published in 2023 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofad078
Abstract: Abstract We investigated single nucleotide polymorphisms (SNPs) possibly involved in immune reconstitution inflammatory syndrome of chronic disseminated candidiasis (IRIS-CDC) through a candidate gene approach and a prospective matched-control study. We found that an SNP located… read more here.
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Published in 2018 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofy157
Abstract: Abstract Background Paradoxical cryptococcosis-associated immune reconstitution inflammatory syndrome (C-IRIS) affects ~25% of human immunodeficiency virus (HIV)-infected patients with cryptococcal meningitis (CM) after they commence antiretroviral therapy (ART) resulting in significant morbidity and mortality. Genomic studies… read more here.
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Published in 2023 at "Journal of pediatric hematology/oncology"
DOI: 10.1097/mph.0000000000002677
Abstract: The FOXN1 gene mutation is a unique disorder that causes the nude severe combined immunodeficiency phenotype. In patients with severe combined immunodeficiency, hematopoietic stem cell transplantation (HSCT) is life-saving if performed earlier. Thymic transplantation is… read more here.
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Published in 2017 at "AIDS"
DOI: 10.1097/qad.0000000000001492
Abstract: Objectives: To investigate the incidence and risk factors of immune reconstitution inflammatory syndrome (IRIS) associated with toxoplasmic encephalitis (TE) in patients starting combination antiretroviral therapy (cART). Design: A historical multicenter cohort study. Methods: We included… read more here.