Folliculin promotes substrate-selective mTORC1 activity by activating RagC to recruit TFE3.
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DOI: 10.1371/journal.pbio.3001594
Abstract: Mechanistic target of rapamycin complex I (mTORC1) is central to cellular metabolic regulation. mTORC1 phosphorylates a myriad of substrates, but how different substrate specificity is conferred on mTORC1 by different conditions remains poorly defined. Here,… read more here.
Keywords: folliculin; tfe3; mtorc1; recruit tfe3 ... See more keywords