RNF168 E3 ligase participates in ubiquitin signaling and recruitment of SLX4 during DNA crosslink repair.
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DOI: 10.1016/j.celrep.2021.109879
Abstract: SLX4/FANCP is a key Fanconi anemia (FA) protein and a DNA repair scaffold for incision around a DNA interstrand crosslink (ICL) by its partner XPF nuclease. The tandem UBZ4 ubiquitin-binding domains of SLX4 are critical… read more here.
Keywords: dna; slx4; rnf168 ligase; recruitment slx4 ... See more keywords