Delayed Accumulation of H3K27me3 on Nascent DNA Is Essential for Recruitment of Transcription Factors at Early Stages of Stem Cell Differentiation.
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DOI: 10.1016/j.molcel.2017.03.006
Abstract: Recruitment of transcription factors (TFs) to repressed genes in euchromatin is essential to activate new transcriptional programs during cell differentiation. However, recruitment of all TFs, including pioneer factors, is impeded by condensed H3K27me3-containing chromatin. Single-cell… read more here.
Keywords: cell differentiation; dna; h3k27me3; differentiation ... See more keywords