Neural-network dose-prediction for rectal spacer stratification in dose-escalated prostate radiotherapy.
Sign Up to like & getrecommendations! Published in 2022 at "Medical physics"
DOI: 10.1002/mp.15575
Abstract: PURPOSE To develop a knowledge-based decision-support system capable of stratifying patients for rectal spacer (RS) insertion based on neural-network-predicted rectal dose, reducing the need for time- and resource-intensive radiotherapy (RT) planning. METHODS Forty four patients… read more here.
Keywords: risk; dose; network; neural network ... See more keywords
One-year clinical outcomes of MR-guided stereotactic body radiation therapy with rectal spacer for patients with localized prostate cancer
Sign Up to like & getrecommendations! Published in 2024 at "World Journal of Urology"
DOI: 10.1007/s00345-024-04784-x
Abstract: Background and purpose This prospective study aimed to investigate adaptive magnetic resonance (MR)-guided stereotactic body radiation therapy (MRgSBRT) with rectal spacer for localized prostate cancer (PC) and report 1-year clinical outcomes. Materials and methods Thirty-four… read more here.
Keywords: rectal spacer; year; prostate cancer; spacer ... See more keywords
Who Benefits From a Prostate Rectal Spacer? Secondary Analysis of a Phase III Trial.
Sign Up to like & getrecommendations! Published in 2020 at "Practical radiation oncology"
DOI: 10.1016/j.prro.2019.12.011
Abstract: PURPOSE/OBJECTIVE(S) Previously a phase III trial of a hydrogel rectal spacer during prostate RT found decreased toxicity and a clinically significant improvement in bowel quality of life (QOL) at 3-years by Expanded Prostate Cancer Index… read more here.
Keywords: rectal spacer; trial; spacer; iii trial ... See more keywords
Impact of rectal spacer on toxicity reduction in men treated with proton versus photon therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2022.40.6_suppl.247
Abstract: 247 Background: Dose escalation in prostate cancer (PCa) radiotherapy (RT) is limited by toxicity to surrounding tissue, including the rectum. Rectal spacers improve bowel toxicity in men treated with photons (i.e. IMRT). However, the relative… read more here.
Keywords: rectal spacer; toxicity; men treated; photon ... See more keywords
Case report of the first use of a hydrogel rectal spacer for prostate cancer reirradiation via LDR brachytherapy: applications and technical notes
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2025.1494304
Abstract: Introduction Prostate cancer remains a prevalent malignancy among men, often necessitating innovative therapeutic strategies for effective management of recurrent cases. This article examines the critical role of a biodegradable hydrogel spacer, which creates a temporary… read more here.
Keywords: rectal spacer; prostate; prostate cancer; case ... See more keywords
Rectal spacer use and overall long-term healthcare costs: payer perspective
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2025.1654925
Abstract: Introduction Rectal spacers (RS), when used in prostate cancer (PCa) patients treated with radiotherapy (RT), reduce radiation dose to the rectum. While RS incur additional upfront cost, they may result in long-term cost-savings by reducing… read more here.
Keywords: rectal spacer; term; long term; spacer use ... See more keywords