Defining how multiple lipid species interact with inward rectifier potassium (Kir2) channels
Sign Up to like & getrecommendations! Published in 2020 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1918387117
Abstract: Significance Ion channels form pores that allow for the selective transport of ions across cell membranes, generating electrical signals in response to a variety of signals. Inward rectifier potassium (Kir) channels in particular are regulated… read more here.
Keywords: kir2; rectifier potassium; lipid species; membrane ... See more keywords
P938Regulation of the delayed rectifier potassium current during the adrenergic adaptation of cardiomyocytes
Sign Up to like & getrecommendations! Published in 2020 at "Europace"
DOI: 10.1093/europace/euaa162.191
Abstract: Supported by the ÚNKP-19-3 New National Excellence program of the Ministry for Innovation and Technology Adaptation of the human heart to physical activity is a complex mechanism that includes the change of heart rate, morphology… read more here.
Keywords: delayed rectifier; stimulation; group; rectifier potassium ... See more keywords
Inward Rectifier Potassium Channels: Membrane Lipid-Dependent Mechanosensitive Gates in Brain Vascular Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.869481
Abstract: Cerebral arteries contain two primary and interacting cell types, smooth muscle (SMCs) and endothelial cells (ECs), which are each capable of sensing particular hemodynamic forces to set basal tone and brain perfusion. These biomechanical stimuli… read more here.
Keywords: kir2 channels; potassium channels; inward rectifier; rectifier potassium ... See more keywords
Pharmacological Inhibition of Inward Rectifier Potassium Channels Induces Lethality in Larval Aedes aegypti
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DOI: 10.3390/insects9040163
Abstract: The inward rectifier potassium (Kir) channels play key roles in the physiology of mosquitoes and other insects. Our group, among others, previously demonstrated that small molecule inhibitors of Kir channels are promising lead molecules for… read more here.
Keywords: kir; kir channels; rectifier potassium; pharmacological inhibition ... See more keywords
From in silico to in vitro: a trip to reveal flavonoid binding on the Rattus norvegicus Kir6.1 ATP-sensitive inward rectifier potassium channel
Sign Up to like & getrecommendations! Published in 2018 at "PeerJ"
DOI: 10.7717/peerj.4680
Abstract: Background ATP-sensitive inward rectifier potassium channels (Kir), are a potassium channel family involved in many physiological processes. KATP dysfunctions are observed in several diseases such as hypoglycaemia, hyperinsulinemia, Prinzmetal angina–like symptoms, cardiovascular diseases. Methods A… read more here.
Keywords: sensitive inward; potassium channel; atp sensitive; rectifier potassium ... See more keywords