Association of Body Mass Index With 21-Gene Recurrence Score Among Women With Estrogen Receptor–Positive, ERBB2–Negative Breast Cancer
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DOI: 10.1001/jamanetworkopen.2022.43935
Abstract: Key Points Question Is high body mass index (BMI) a factor associated with a high 21-gene recurrence score in estrogen receptor (ER)–positive, ERBB2-negative (formerly HER2 or HER2/neu) breast cancer, especially in younger patients (≤45 years)… read more here.
Keywords: recurrence score; breast cancer; cancer; gene recurrence ... See more keywords
Association of Neighborhood-Level Household Income With 21-Gene Recurrence Score and Survival Among Patients With Estrogen Receptor–Positive Breast Cancer
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.0179
Abstract: Key Points Question Do household income levels factor into 21-gene recurrence score (RS) and mortality among patients with estrogen receptor (ER)-positive breast cancer? Findings In this cohort study involving 119 478 women, low income was associated… read more here.
Keywords: household income; recurrence score; patients estrogen; gene recurrence ... See more keywords
Chemotherapy decisions and patient experience with the recurrence score assay for early‐stage breast cancer
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DOI: 10.1002/cncr.30324
Abstract: The 21‐gene recurrence score (RS) assay stratifies early‐stage, estrogen receptor–positive breast cancer by recurrence risk. Few studies have examined the ways in which physicians use the RS to recommend adjuvant systemic chemotherapy or patients' experiences… read more here.
Keywords: recurrence score; recurrence; breast cancer; early stage ... See more keywords
Associations between use of the 21‐gene recurrence score assay and chemotherapy regimen selection in a statewide registry
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DOI: 10.1002/cncr.30429
Abstract: The 21‐gene recurrence score (RS) assay predicts response to adjuvant chemotherapy in patients with early‐stage, hormone receptor‐positive, human epidermal growth factor receptor 2 (HER2)‐negative invasive breast cancer, but to the authors' knowledge, the role of… read more here.
Keywords: chemotherapy; chemotherapy regimen; gene recurrence; recurrence score ... See more keywords
Impact of TAILORx on chemotherapy prescribing and 21‐gene recurrence score–guided treatment costs in a population‐based cohort of patients with breast cancer
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DOI: 10.1002/cncr.33982
Abstract: The trial assigning individualized options for treatment (Rx) (TAILORx) confirmed the predictive value of the 21‐gene recurrence score (RS) assay in hormone receptor (HR)–positive, HER2‐negative, node‐negative breast cancer and established thresholds for chemotherapy benefit in… read more here.
Keywords: cancer; breast cancer; guided treatment; treatment ... See more keywords
Correlation of the Ki67 Working Group prognostic risk categories with the Oncotype DX Recurrence Score in early breast cancer
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DOI: 10.1002/cncr.34426
Abstract: The relationship between Ki67 assessed by immunohistochemistry (IHC) and the Oncotype DX Recurrence Score (RS) is unclear. The objective of this study was to determine the correlation between the 21‐gene RS and IHC‐measured Ki67 with… read more here.
Keywords: oncotype recurrence; recurrence score; ki67 working; working group ... See more keywords
Prediction of Oncotype Dx recurrence score using clinical parameters: A comparison of available tools and a simple predictor based on grade and progesterone receptor.
Sign Up to like & getrecommendations! Published in 2019 at "Hematology/oncology and stem cell therapy"
DOI: 10.1016/j.hemonc.2019.02.001
Abstract: OBJECTIVE/BACKGROUND The Oncotype Dx test is a genomic test currently used in clinical practice to predict the risk of disease recurrence in estrogen receptor (ER)-positive, HER2-negative breast cancer patients with axillary lymph node-negative or micrometastatic… read more here.
Keywords: recurrence score; recurrence; simple predictor; test ... See more keywords
Evaluation oncotype DX® 21‐gene recurrence score and clinicopathological parameters: a single institutional experience
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DOI: 10.1111/his.14863
Abstract: Oncotype DX recurrence score (RS) is a clinically validated assay, which predicts the likelihood of disease recurrence in oestrogen receptor‐positive/HER2‐negative (ER+/HER2−) breast cancer (BC). In this study we aimed to compare the performance of Oncotype… read more here.
Keywords: clinicopathological parameters; oncotype gene; recurrence score; recurrence ... See more keywords
Abstract P1-09-14: Breast carcinoma with 21-gene recurrence score lower than 18: Rate of distant metastases in a large series with clinical follow-up
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs16-p1-09-14
Abstract: Background: The 21-gene recurrence score (RS) estimates the likelihood of distant recurrence and the benefit from chemotherapy in patients with early-stage node-negative, estrogen receptor (ER)-positive, HER2-negative breast carcinoma. The use of the assay resulted in… read more here.
Keywords: gene recurrence; breast; breast cancer; recurrence score ... See more keywords
Abstract PD7-05: How 21-gene recurrence score assay is being used to individualize adjuvant chemotherapy recommendations in ER+/HER2 -node positive breast cancer -A national cancer data base study
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs16-pd7-05
Abstract: Introduction: The 21-gene Recurrence Score (RS) assay has been shown in retrospective studies to predict benefit of adjuvant chemotherapy (AC) in node positive (N+) breast cancer (BC) patients (pts). This study evaluates the trends and… read more here.
Keywords: gene recurrence; breast cancer; recurrence score; cancer ... See more keywords
Abstract P2-14-20: The impact of recurrence score versus sentinel lymph node biopsy on treatment decisions in early breast cancer
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs19-p2-14-20
Abstract: Rationale: Choosing Wisely: In an era of genomic medicine, what role does nodal information play in decisions regarding adjuvant chemotherapy for early-stage, hormone receptor-positive breast cancer ? Authors: Fowler RL, Lew KP, Dizon DS, Ciambella… read more here.
Keywords: breast; breast cancer; recurrence score; cancer ... See more keywords