LAUSR

Recurrent activating mutations of PPAR gamma associated with luminal bladder tumors.

Sign Up to like & get
recommendations!
0 Published in 2019 at "Nature Communications"

DOI: 10.2210/pdb6fzy/pdb

Abstract: The upregulation of PPARγ/RXRα transcriptional activity has emerged as a key event in luminal bladder tumors. It renders tumor cell growth PPARγ-dependent and modulates the tumor microenvironment to favor escape from immuno-surveillance. The activation of… read more here.

Keywords: bladder tumors; recurrent activating; luminal bladder; bladder ... See more keywords