Articles with "recurrent driver" as a keyword



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Isolation of CD4+ T cells specific for neoantigens created by recurrent driver mutations in non-small cell lung cancer (NSCLC) and melanoma.

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Published in 2018 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2018.36.15_suppl.12054

Abstract: 12054Background: T cells specific for neoantigens encoded by mutated genes are increasingly recognized as mediators of tumor destruction after immune checkpoint inhibitor therapy or adoptive cell transfer. Unfortunately, almost all neoantigens result from random mutations… read more here.

Keywords: cells specific; specific neoantigens; recurrent driver; driver mutations ... See more keywords