Comprehensive genetic alteration profiling in primary and recurrent glioblastoma
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DOI: 10.1007/s11060-018-03070-2
Abstract: IntroductionGlioblastoma (GBM) is heterogeneous and underlying genomic profiles influence evolution, resistance, and therapeutic responses. While extensive knowledge regarding genomic profiling of primary GBM exists, there remains a lack of understanding of genomic differences in recurrent… read more here.
Keywords: primary recurrent; gbm; recurrent gbm; comprehensive genetic ... See more keywords
P13.11 Transcriptional CDK inhibitors, CYC065 and THZ1 promote apoptosis in preclinical models of primary and recurrent GBM tumour cells and glioma stem cells
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DOI: 10.1093/neuonc/noab180.119
Abstract: Activation of cyclin-dependent kinases (CDKs) contributes to the uncontrolled proliferation of tumour cells. Genomic alterations that lead to the constitutive activation of CDKs are a feature of many tumours including glioblastoma (GBM), the most common… read more here.
Keywords: primary recurrent; cdk inhibitors; apoptosis; gbm ... See more keywords
NCOG-10. SURGERY FOR RECURRENT GBM: A RETROSPECTIVE CASE-CONTROL STUDY
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DOI: 10.1093/neuonc/noac209.763
Abstract: The role of surgery in recurrent GBM remains a controversial topic. The goal of this study was to perform a case-control analysis including time to tumor recurrence as an additional prognostic factor in order to… read more here.
Keywords: surgery recurrent; surgery; recurrent gbm; recurrence ... See more keywords
5-Aminolevulinic Acid False-Positive Rates in Newly Diagnosed and Recurrent Glioblastoma: Do Pseudoprogression and Radionecrosis Play a Role? A Meta-Analysis
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DOI: 10.3389/fonc.2022.848036
Abstract: Background Several studies have confirmed the impact of 5-aminolevulinic acid (5-ALA) on the extent of resection in newly diagnosed glioblastoma (GBM). However, there are controversies on the 5-ALA fluorescence status in recurrent GBM surgery, with… read more here.
Keywords: analysis; recurrent gbm; newly diagnosed; recurrent ... See more keywords