Toxic effects of dimethyl sulfoxide on red blood cells, platelets, and vascular endothelial cells in vitro
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12193
Abstract: Dimethyl sulfoxide (DMSO) is widely used in biological studies as a cryoprotective agent for cells and tissues, and also for cryopreserved platelets (PLTs). However, few data on the toxic effects of DMSO following intravenous infusion… read more here.
Keywords: red blood; vascular endothelial; toxic effects; dimethyl sulfoxide ... See more keywords
Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding
Sign Up to like & getrecommendations! Published in 2025 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.70005
Abstract: Red blood cells (RBCs) have emerged as reservoirs of microRNAs (miRNAs) in the circulatory system, challenging the traditional view of their nucleic acid absence. This study investigates the miRNA profiles and stability of both native… read more here.
Keywords: cells could; could protect; blood cells; red blood ... See more keywords
Versatile Red Blood Cells for Triple‐Negative Breast Cancer Treatment via Stepwise Photoactivations
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202201690
Abstract: Phototherapies have many advantages for triple‐negative breast cancer (TNBC) treatment. However, their effects are often limited by short blood circulation time, poor tumor selectivity and weak penetration of phototherapeutic agents, and tumor hypoxia. For overcoming… read more here.
Keywords: red blood; triple negative; breast cancer; blood ... See more keywords
A Dynamic Membrane‐Active Glycopeptide for Enhanced Protection of Human Red Blood Cells against Freeze‐Stress
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202202516
Abstract: Intracellular delivery of freezing‐tolerant trehalose is crucial for cryopreservation of red blood cells (RBCs) and previous strategies based on membrane‐disruptive activity usually generate severe hemolysis. Herein, a dynamic membrane‐active glycopeptide is developed by grafting with… read more here.
Keywords: dynamic membrane; glycopeptide; red blood; blood cells ... See more keywords
Converting Red Blood Cells to Efficient Microreactors for Blood Detoxification.
Sign Up to like & getrecommendations! Published in 2017 at "Advanced materials"
DOI: 10.1002/adma.201603673
Abstract: A simple method to convert red blood cells (RBCs) into efficient microreactors is reported. Triton X-100 is employed at finely tuned concentrations to render RBCs highly permeable to substrates, while low concentrations of glutaraldehyde are… read more here.
Keywords: red blood; efficient microreactors; blood detoxification; blood ... See more keywords
Detecting Swelling States of Red Blood Cells by “Cell–Fluid Coupling Spectroscopy”
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Science"
DOI: 10.1002/advs.201600238
Abstract: Red blood cells are “shaken” with a holographic optical tweezer array. The flow generated around cells due to the periodic optical forcing is measured with an optically trapped “detector” particle located in the cell vicinity.… read more here.
Keywords: red blood; swelling states; spectroscopy; detecting swelling ... See more keywords
Biomorphic Engineering of Multifunctional Polylactide Stomatocytes toward Therapeutic Nano‐Red Blood Cells
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Science"
DOI: 10.1002/advs.201801678
Abstract: Abstract Morphologically discrete nanoarchitectures, which mimic the structural complexity of biological systems, are an increasingly popular design paradigm in the development of new nanomedical technologies. Herein, engineered polymeric stomatocytes are presented as a structural and… read more here.
Keywords: red blood; multifunctional polylactide; blood cells; biomorphic engineering ... See more keywords
Mature Red Blood Cells Contain Long DNA Fragments and Could Acquire DNA from Lung Cancer Tissue
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202206361
Abstract: Red blood cells (RBC) are commonly known as cells with no nucleus or mitochondria and are assumed to be a transportation vehicle. This study confirms that RBC contain long DNA fragments inside with stain by… read more here.
Keywords: cell; dna; red blood; blood cells ... See more keywords
An Optimized Human Erythroblast Differentiation System Reveals Cholesterol‐Dependency of Robust Production of Cultured Red Blood Cells Ex Vivo
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202303471
Abstract: The generation of cultured red blood cells (cRBCs) ex vivo represents a potentially unlimited source for RBC transfusion and other cell therapies. Human cRBCs can be generated from the terminal differentiation of proliferating erythroblasts derived… read more here.
Keywords: differentiation; human plasma; cultured red; red blood ... See more keywords
An Optimized Human Erythroblast Differentiation System Reveals Cholesterol‐Dependency of Robust Production of Cultured Red Blood Cells Ex Vivo (Adv. Sci. 22/2024)
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202470126
Abstract: Red Blood Cell Production In article number 2303471, Senquan Liu, Linzhao Cheng, and co‐workers reveal the crucial role of lipid metabolism during human terminal erythropoiesis and develop a chemically‐defined medium for ex vivo red blood… read more here.
Keywords: erythroblast differentiation; optimized human; human erythroblast; blood ... See more keywords
Centrifugation‐free washing: A novel approach for removing immunoglobulin A from stored red blood cells
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Hematology"
DOI: 10.1002/ajh.25026
Abstract: Washed red blood cells (RBCs) are indicated for immunoglobulin A (IgA) deficient recipients. Centrifugation‐based cell processors commonly used by hospital blood banks cannot consistently reduce IgA below the recommended levels, hence double washing is frequently… read more here.
Keywords: red blood; washing system; centrifugation; blood ... See more keywords