P038 Donor specific anti-a titer for abo incompatible (ABOi) living kidney transplantation
Sign Up to like & getrecommendations! Published in 2018 at "Human Immunology"
DOI: 10.1016/j.humimm.2018.07.096
Abstract: To increase the donor options for our active living kidney donor program, candidates who are blood group B may receive a living donor transplant from a non-A1 or non-A1B donor. ABO incompatible donors (ABOi) are… read more here.
Keywords: abo; red cells; donor; living kidney ... See more keywords
An immortalized adult human erythroid line facilitates sustainable and scalable generation of functional red cells
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms14750
Abstract: With increasing worldwide demand for safe blood, there is much interest in generating red blood cells in vitro as an alternative clinical product. However, available methods for in vitro generation of red cells from adult… read more here.
Keywords: adult; line; immortalized adult; red cells ... See more keywords
Oxidative stress and phosphatidylserine exposure in red cells from patients with sickle cell anaemia
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Haematology"
DOI: 10.1111/bjh.15441
Abstract: Phosphatidylserine (PS) exposure increases as red cells age, and is an important signal for the removal of senescent cells from the circulation. PS exposure is elevated in red cells from sickle cell anaemia (SCA) patients… read more here.
Keywords: phosphatidylserine exposure; exposure; red cells; stress ... See more keywords
Percentage of hypochromic red cells as a potential screening test to evaluate iron status in blood donors
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Laboratory Hematology"
DOI: 10.1111/ijlh.13009
Abstract: Haemoglobin (Hb) levels are used to assess eligibility for blood donation but are not correlated with iron status. The percentage of hypochromic red cells (%Hypo‐He) has been suggested as a useful screening parameter for iron… read more here.
Keywords: iron status; hypochromic red; percentage hypochromic; red cells ... See more keywords
“Rare” reagent red cells: rare no longer?
Sign Up to like & getrecommendations! Published in 2018 at "Transfusion"
DOI: 10.1111/trf.14958
Abstract: A ntibody screening during pretransfusion testing is critical to avoid transfusion of incompatible blood and subsequent acute or delayed hemolytic transfusion reactions. Alloantibody identification currently relies on reagent red blood cells obtained from group O… read more here.
Keywords: cells rare; reagent red; red cells; transfusion ... See more keywords
Pharmacogenomics with red cells: a model to study protein variants of drug transporter genes
Sign Up to like & getrecommendations! Published in 2020 at "Vox Sanguinis"
DOI: 10.1111/vox.12999
Abstract: The PharmacoScan pharmacogenomics platform screens for variation in genes that affect drug absorption, distribution, metabolism, elimination, immune adverse reactions and targets. Among the 1,191 genes tested on the platform, 12 genes are expressed in the… read more here.
Keywords: cells model; model study; red cells; drug ... See more keywords
Red cells manufactured from lipaemic whole blood donations: Do they have higher haemolysis?
Sign Up to like & getrecommendations! Published in 2022 at "Vox Sanguinis"
DOI: 10.1111/vox.13366
Abstract: Lipaemia in blood donations is thought to influence haemolysis in stored red blood cell (RBC) components. Higher lipid concentrations are believed to increase red cell fragility, exacerbating haemolysis during collection and subsequent red cell storage.… read more here.
Keywords: red cells; cells manufactured; haemolysis; haemolysis red ... See more keywords
A Novel Approach to Assess Capacities of Red Cells in Dissolving Oxygen and Carrying Oxygen Based on a Portable Near-Infrared Spectroscopy Device
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-124003
Abstract: Oxygen dissolving and dissovling capabilities ( briefly, ODC and OCC) are very valuable to assess the functions in oxygen transport and metabolism of red cells, especially for research on, diagnosis, and evaluating therapeutic effects of… read more here.
Keywords: oxygen; red cells; blood; solution ... See more keywords
Sensing of red blood cells with decreased membrane deformability by the human spleen.
Sign Up to like & getrecommendations! Published in 2018 at "Blood advances"
DOI: 10.1182/bloodadvances.2018024562
Abstract: The current paradigm in the pathogenesis of several hemolytic red blood cell disorders is that reduced cellular deformability is a key determinant of splenic sequestration of affected red cells. Three distinct features regulate cellular deformability:… read more here.
Keywords: red blood; membrane deformability; red cells; deformability ... See more keywords
The effect of xanthine oxidase and hypoxanthine on the permeability of red cells from patients with sickle cell anemia
Sign Up to like & getrecommendations! Published in 2018 at "Physiological Reports"
DOI: 10.14814/phy2.13626
Abstract: Red cells from patients with sickle cell anemia (SCA) are under greater oxidative challenge than those from normal individuals. We postulated that oxidants generated by xanthine oxidase (XO) and hypoxanthine (HO) contribute to the pathogenesis… read more here.
Keywords: patients sickle; red cells; effect; cells patients ... See more keywords
Micro-Raman Spectroscopy Analysis of Optically Trapped Erythrocytes in Jaundice
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.00821
Abstract: Derangements in bilirubin metabolism and/or dysfunctions in the hepato-biliary system lead to the unhealthy buildup of bilirubin in blood, resulting in jaundice. During the course of this disorder, circulating red cells are invariably subjected to… read more here.
Keywords: raman; jaundice; micro raman; red cells ... See more keywords