Discovery of a Redox-Activatable Chemical Probe for Detection of Cyclooxygenase-2 in Cells and Animals.
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DOI: 10.1021/acschembio.1c00961
Abstract: Cyclooxygenase-2 (COX-2) expression is up-regulated in inflammatory tissues and many premalignant and malignant tumors. Assessment of COX-2 protein in vivo, therefore, promises to be a powerful strategy to distinguish pathologic cells from normal cells in… read more here.
Keywords: discovery redox; redox activatable; cyclooxygenase; pathologic tissues ... See more keywords