Autophagy and the redox connection: Virtual collection Vol 2
Sign Up to like & getrecommendations! Published in 2017 at "Redox Biology"
DOI: 10.1016/j.redox.2016.10.005
Abstract: The Nobel Prize of Physiology or Medicine for 2016 has been awarded to Yoshinori Ohsumi for his discoveries of the mechanisms of autophagy. The phenomenon of autophagy was first observed in the 1950-60s in a… read more here.
Keywords: autophagy redox; redox; physiology; redox biology ... See more keywords
Sexual dimorphisms in redox biology
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DOI: 10.1016/j.redox.2020.101533
Abstract: Sex differences have been reported for all major diseases, including cardiovascular diseases [1,2] and cardiometabolic disorders [3], hypertension [4,5], obesity [6], diabetes and diabetic complications [7], neurodegenerative disorders [8,9], autoimmune diseases [10,11] and cancers [12].… read more here.
Keywords: sex differences; redox biology; sex; biology ... See more keywords
Piperazine-Fused Cyclic Disulfides Unlock High-Performance Bioreductive Probes of Thioredoxins and Bifunctional Reagents for Thiol Redox Biology.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.3c11153
Abstract: We report piperazine-fused six-membered-cyclic disulfides as redox substrates that unlock best-in-class bioreduction probes for live cell biology, since their self-immolation after reduction is unprecedentedly rapid. We develop scalable, diastereomerically pure, six-step syntheses that access four… read more here.
Keywords: bifunctional reagents; redox biology; biology; fused cyclic ... See more keywords
Recent innovations in targeting redox biology for therapeutics.
Sign Up to like & getrecommendations! Published in 2025 at "British journal of pharmacology"
DOI: 10.1111/bph.70156
Abstract: Redox signalling governs key physiological and pathological processes, offering diverse therapeutic targets across disease contexts. This editorial introduces a special issue of the British Journal of Pharmacology highlighting recent advances in redox biology, including novel… read more here.
Keywords: redox biology; pharmacology; biology; recent innovations ... See more keywords
Abstract Tu123: Redox Biology of the Mitochondrial Protein mitoNEET and Ascorbate
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DOI: 10.1161/res.135.suppl_1.tu123
Abstract: Background: It has been proposed that mitoNEET is an Fe-S transfer/repair enzyme, playing a role under conditions of oxidative stress. mitoNEET protects mitochondria against oxidative stress in cardiomyocytes. Loss of mitoNEET is linked with age-related… read more here.
Keywords: redox biology; mitoneet ascorbate; biology; mitoneet ... See more keywords
Understanding the Redox Biology of Selenium in the Search of Targeted Cancer Therapies
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DOI: 10.3390/antiox9050420
Abstract: Selenium (Se) is an essential trace nutrient required for optimal human health. It has long been suggested that selenium has anti-cancer properties. However, clinical trials have shown inconclusive results on the potential of Se to… read more here.
Keywords: understanding redox; biology selenium; redox biology; biology ... See more keywords