Metformin selectively targets redox control of complex I energy transduction
Sign Up to like & getrecommendations! Published in 2018 at "Redox Biology"
DOI: 10.1016/j.redox.2017.08.018
Abstract: Many guanide-containing drugs are antihyperglycaemic but most exhibit toxicity, to the extent that only the biguanide metformin has enjoyed sustained clinical use. Here, we have isolated unique mitochondrial redox control properties of metformin that are… read more here.
Keywords: metformin selectively; redox control; energy transduction;
Enzymatic X-ray absorption spectroelectrochemistry.
Sign Up to like & getrecommendations! Published in 2022 at "Faraday discussions"
DOI: 10.1039/d1fd00079a
Abstract: The ability to observe the changes that occur at an enzyme active site during electrocatalysis can provide very valuable information for understanding the mechanism and ultimately aid in catalyst design. Herein, we discuss the development… read more here.
Keywords: ray absorption; ray; redox control; electrochemistry ... See more keywords
Personalized nutrition in ageing society: redox control of major-age related diseases through the NutRedOx Network (COST Action CA16112)
Sign Up to like & getrecommendations! Published in 2019 at "Free Radical Research"
DOI: 10.1080/10715762.2019.1572890
Abstract: Abstract A healthy ageing process is important when it is considered that one-third of the population of Europe is already over 50 years old, although there are regional variations. This proportion is likely to increase… read more here.
Keywords: age; redox control; nutrition ageing; nutredox network ... See more keywords
Redox Control of Vascular Function
Sign Up to like & getrecommendations! Published in 2017 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atvbaha.117.309945
Abstract: In the past several years, a significant body of work has been published in ATVB about new research in the field of vascular biology and redox signaling. We would like to highlight new publications that… read more here.
Keywords: research; redox; vascular function; control vascular ... See more keywords
Redox control in the pathophysiology of influenza virus infection
Sign Up to like & getrecommendations! Published in 2020 at "BMC Microbiology"
DOI: 10.1186/s12866-020-01890-9
Abstract: Triggered in response to external and internal ligands in cells and animals, redox homeostasis is transmitted via signal molecules involved in defense redox mechanisms through networks of cell proliferation, differentiation, intracellular detoxification, bacterial infection, and… read more here.
Keywords: infection; redox; redox control; influenza virus ... See more keywords
Genetic Variations on Redox Control in Cardiometabolic Diseases: The Role of Nrf2
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11030507
Abstract: The transcription factor Nrf2 is a master regulator of multiple cytoprotective genes that maintain redox homeostasis and exert anti-inflammatory functions. The Nrf2-Keap1 signaling pathway is a paramount target of many cardioprotective strategies, because redox homeostasis… read more here.
Keywords: redox control; variations redox; control cardiometabolic; genetic variations ... See more keywords
Towards Initial Indications for a Thiol-Based Redox Control of Arabidopsis 5-Aminolevulinic Acid Dehydratase
Sign Up to like & getrecommendations! Published in 2018 at "Antioxidants"
DOI: 10.3390/antiox7110152
Abstract: Thiol-based redox control is one of the important posttranslational mechanisms of the tetrapyrrole biosynthesis pathway. Many enzymes of the pathway have been shown to interact with thioredoxin (TRX) and Nicotinamide adenine dinucleotide phosphate (NADPH)-dependent thioredoxin… read more here.
Keywords: based redox; aminolevulinic acid; thiol based; acid dehydratase ... See more keywords
Mechano-redox control of integrin de-adhesion
Sign Up to like & getrecommendations! Published in 2018 at "eLife"
DOI: 10.7554/elife.34843
Abstract: How proteins harness mechanical force to control function is a significant biological question. Here we describe a human cell surface receptor that couples ligand binding and force to trigger a chemical event which controls the… read more here.
Keywords: mechano redox; control; adhesion; ligand binding ... See more keywords