Dual Intratumoral Redox/Enzyme-Responsive NO-Releasing Nanomedicine for the Specific, High-Efficacy, and Low-Toxic Cancer Therapy.
Sign Up to like & getrecommendations! Published in 2018 at "Advanced materials"
DOI: 10.1002/adma.201704490
Abstract: Chemotherapy suffers numbers of limitations including poor drug solubility, nonspecific biodistribution, and inevitable adverse effects on normal tissues. Tumor-targeted delivery and intratumoral stimuli-responsive release of drugs by nanomedicines are considered to be highly promising in… read more here.
Keywords: dual intratumoral; responsive releasing; redox enzyme; intratumoral redox ... See more keywords
Fluorescent carbon dot‐gated multifunctional mesoporous silica nanocarriers for redox/enzyme dual‐responsive targeted and controlled drug delivery and real‐time bioimaging
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2017.03.019
Abstract: Graphical abstract Figure. No caption available. ABSTRACT A distinctive and personalized nanocarrier is described here for controlled and targeted antitumor drug delivery and real‐time bioimaging by combining a redox/enzyme dual‐responsive disulfide‐conjugated carbon dot with mesoporous… read more here.
Keywords: dual responsive; redox enzyme; delivery; drug ... See more keywords