Intracellular Mutual Promotion of Redox Homeostasis Regulation and Iron Metabolism Disruption for Enduring Chemodynamic Therapy
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202010390
Abstract: Intracellular redox homeostasis and the iron metabolism system in tumor cells are closely associated with the limited efficacy of chemodynamic therapy (CDT). Despite extensive attempts, maintaining high levels of intracellular catalysts (free iron) and reactants… read more here.
Keywords: chemodynamic therapy; iron; redox homeostasis; iron metabolism ... See more keywords
Methane enhances aluminum resistance in alfalfa seedlings by reducing aluminum accumulation and reestablishing redox homeostasis
Sign Up to like & getrecommendations! Published in 2017 at "BioMetals"
DOI: 10.1007/s10534-017-0040-z
Abstract: Methane (CH4) is emerging as a candidate of signal molecule recently. However, whether or how CH4 enhances plant adaptation to aluminum (Al)-contaminated environment is still unknown. In this report, the physiological roles and possible molecular… read more here.
Keywords: alfalfa seedlings; accumulation; redox homeostasis; reestablishing redox ... See more keywords
The Reducible Disulfide Proteome of Synaptosomes Supports a Role for Reversible Oxidations of Protein Thiols in the Maintenance of Neuronal Redox Homeostasis
Sign Up to like & getrecommendations! Published in 2020 at "Neurochemical Research"
DOI: 10.1007/s11064-020-03046-7
Abstract: The mechanisms by which neurons maintain redox homeostasis, disruption of which is linked to disease, are not well known. Hydrogen peroxide, a major cellular oxidant and neuromodulator, can promote reversible oxidations of protein thiols but… read more here.
Keywords: reducible disulfide; protein thiols; redox homeostasis; reversible oxidations ... See more keywords
Nanotherapeutics interfere with cellular redox homeostasis for highly improved photodynamic therapy.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2019.119500
Abstract: Redox homeostasis inside malignant cells is a defense mechanism against the reactive oxygen species (ROS)-induced therapy means, but little importance has been paid to this innate barrier. The present study intends to make cancer cells… read more here.
Keywords: homeostasis; cellular redox; redox homeostasis; photodynamic therapy ... See more keywords
Effects of resistance exercise training on redox homeostasis in older adults. A systematic review and meta-analysis
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DOI: 10.1016/j.exger.2020.111012
Abstract: BACKGROUND Resistance exercise training (RET) has proven effective at reducing the risk of chronic disease in older populations, and it appears to regulate redox homeostasis. AIMS To determine the effects of RET on redox homeostasis… read more here.
Keywords: homeostasis; homeostasis older; redox homeostasis; review ... See more keywords
Double deficiency of isocitrate dehydrogenase-1 and glucose 6-phosphate dehydrogenase hinders growth and development in C. elegans due to altered metabolism and redox homeostasis
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.04.173
Abstract: Growth and development are affected by cellular redox homeostasis which is modulated partly by NADPH status. Both glucose 6-phosphate dehydrogenase (G6PD) and isocitrate dehydrogenase1 (IDH1) are responsible for the regeneration of NADPH in cells. To… read more here.
Keywords: dehydrogenase; redox homeostasis; deficient; g6pd idh1 ... See more keywords
Growth defects and metabolic alterations in IDH-1 and G6PD double-deficient Caenorhabditis elegans due to severe imbalance of redox homeostasis
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.10.204
Abstract: NADPH plays an indispensable role in normal cellular physiology by maintaining redox homeostasis and providing reducing power for reductive biosynthesis. Isocitrate dehydrogenase-1 (IDH1) and glucose 6-phosphate dehydrogenase (G6PD) are the two major NADPH-generating enzymes in… read more here.
Keywords: redox homeostasis; g6pd idh1; double deficient; deficient ... See more keywords
Gene expression profiling of early Parkinson’s disease patient reveals redox homeostasis
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DOI: 10.1016/j.neulet.2021.135893
Abstract: Parkinson's disease (PD) is slowly progressive. Due to the lack of specific and sensitive biomarkers, the majority of PD patients are in the advanced stages when diagnosed. This study aimed to investigate biomarkers for early… read more here.
Keywords: gene; redox homeostasis; gene expression; parkinson disease ... See more keywords
Constitutive activation of Nrf2 induces a stable reductive state in the mouse myocardium
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DOI: 10.1016/j.redox.2017.04.038
Abstract: Redox homeostasis regulates key cellular signaling pathways in both physiology and pathology. The cell's antioxidant response provides a defense against oxidative stress and establishes a redox tone permissive for cell signaling. The molecular regulation of… read more here.
Keywords: state; redox homeostasis; antioxidant response; nrf2 ... See more keywords
Exercise, redox homeostasis and the epigenetic landscape
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DOI: 10.1016/j.redox.2020.101477
Abstract: Physical exercise represents one of the strongest physiological stimuli capable to induce functional and structural modifications in all biological systems. Indeed, beside the traditional genetic mechanisms, physical exercise can modulate gene expression through epigenetic modifications,… read more here.
Keywords: redox homeostasis; homeostasis epigenetic; exercise redox; epigenetic landscape ... See more keywords
Redox Homeostasis Alteration in Endothelial Mechanotransduction Monitored by Dual Stretchable Electrochemical Sensors.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c01227
Abstract: In vivo, endothelial cells are permanently subjected to dynamic cyclic stretch and adapt to it through the release of vasoactive substances. Among them, reactive oxygen species (ROS) and nitric oxide (NO) are indispensable redox molecules,… read more here.
Keywords: endothelial mechanotransduction; redox homeostasis; stretchable electrochemical;