Diselenide-crosslinked zwitterionic nanogels with dual redox-labile properties for controlled drug release
Sign Up to like & getrecommendations! Published in 2020 at "Polymer Chemistry"
DOI: 10.1039/d0py00004c
Abstract: Drug delivery systems developed from zwitterionic polymers have intriguing antifouling properties. Combining these with stimuli-responsiveness, we fabricated a new type of zwitterionic nanogel with dual redox-labile properties by copolymerization of 2-methacryloyloxyethyl phosphorylcholine (MPC) and a… read more here.
Keywords: release; dual redox; labile properties; redox labile ... See more keywords
A proximity-based in silico approach to identify redox-labile disulfide bonds: The example of FVIII
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0262409
Abstract: Allosteric disulfide bonds permit highly responsive, transient ‘switch-like’ properties that are ideal for processes like coagulation and inflammation that require rapid and localised responses to damage or injury. Haemophilia A (HA) is a rare bleeding… read more here.
Keywords: proximity based; disulfide; based silico; redox labile ... See more keywords