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Published in 2017 at "Advanced materials"
DOI: 10.1002/adma.201603888
Abstract: Redox reactions can alter the electronic, optical, and magnetic properties of molecules and their ensembles by adding or removing electrons. Here, the developments made over the past 10 years using molecular events are discussed, such…
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Keywords:
molecular systems;
redox responsive;
systems materials;
responsive molecular ... See more keywords
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Published in 2018 at "Macromolecular bioscience"
DOI: 10.1002/mabi.201700339
Abstract: Redox-responsive micelles are versatile nanoplatforms for on-demand drug delivery, but the in situ evaluation of drug release is challenging. Fluorescence resonance energy transfer (FRET) technique shows potential for addressing this, while the aggregation-caused quenching effect…
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Keywords:
redox responsive;
responsive micelles;
drug;
drug release ... See more keywords
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Published in 2018 at "Small"
DOI: 10.1002/smll.201802565
Abstract: Biodegradable polymeric nanoparticles (NPs) have demonstrated significant potential to improve the systemic delivery of RNA interference (RNAi) therapeutics, such as small interfering RNA (siRNA), for cancer therapy. However, the slow and inefficient siRNA release inside…
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Keywords:
redox responsive;
sirna;
cancer therapy;
rnai ... See more keywords
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Published in 2022 at "Small"
DOI: 10.1002/smll.202205062
Abstract: Timely restoration of blood supply after myocardial ischemia is imperative for the treatment of acute myocardial infarction but causes additional myocardial ischemia/reperfusion (MI/R) injury, which has not been hitherto effectively targeted by interventions for MI/R…
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Keywords:
ischemia;
myocardial ischemia;
reperfusion;
redox responsive ... See more keywords
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Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.05.031
Abstract: The oxidation-reduction (redox)-responsive micelle system is based on a diselenide-containing triblock copolymer, poly(ε-caprolactone)-bis(diselenide-methoxy poly(ethylene glycol)/poly(ethylene glycol)-folate) [PCL-(SeSe-mPEG/PEG-FA)2]. This has helped in the development of tumor-targeted delivery for hydrophobic anticancer drugs. The diselenide bond, as a…
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Keywords:
redox responsive;
micelle;
redox;
diselenide containing ... See more keywords
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Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.119760
Abstract: Combination therapy has been developed as an innovative modality for effective cancer therapy. However, the administration of combinatorial therapeutics is limited by the varying pharmacokinetics of different drugs. Although numerous nanoparticles (NPs) can synchronize the…
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Keywords:
redox responsive;
responsive polyprodrug;
delivery;
therapy ... See more keywords
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Published in 2017 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2016.10.089
Abstract: A smart hybrid microenvironment-mediated dual pH/redox-responsive polymeric nanoparticles combined with inorganic calcium phosphate (CaP) was fabricated, which we term as armored nano-chrysalis inspired by butterfly pupa. The nano-chrysalis has an inner core composed of specially…
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Keywords:
redox responsive;
oligosaccharides hyaluronan;
nano chrysalis;
dual redox ... See more keywords
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Published in 2018 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2018.09.025
Abstract: Graphical abstract Figure. No Caption available. Abstract Redox‐responsive polymer dot (PD) were synthesized from disulfide cross‐linked polymers in a carbonized process to allow quenching effects by loading of boron‐dipyrromethene (BODIPY) onto the matrix. The disulfide…
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Keywords:
bodipy;
redox responsive;
fluorescence;
gsh ... See more keywords
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Published in 2019 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2018.12.006
Abstract: Graphical abstract A macro‐photosensitizer with redox‐responsive was synthesized for NIR imaging‐guided photodynamic therapy. Figure. No Caption available. Abstract Efficient delivery of hydrophobic photosensitizer (PS) into tumor cells is a key step for photodynamic therapy (PDT).…
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Keywords:
redox responsive;
photodynamic therapy;
near infrared;
imaging guided ... See more keywords
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Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.01.136
Abstract: In this study, we reported a redox-responsive drug delivery system (DDS) based on heparosan and deoxycholic acid conjugates (HSDs) for effective treatment of laryngopharyngeal carcinoma. The amphiphilic HSDs can self-assemble into stable nanoscale micelles in…
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Keywords:
triggered drug;
redox responsive;
drug delivery;
drug ... See more keywords
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Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.119190
Abstract: Cisplatin is one of the most widely used platinum-based anticancer chemotherapeutic drugs. However, its low solubility, serious side effects and the development of cisplatin resistance limit its further use in the clinic. Controlling the delivery…
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Keywords:
redox responsive;
delivery system;
delivery;
cisplatin ... See more keywords