Redox Signaling in the Right Ventricle.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-63245-2_19
Abstract: Pulmonary hypertension is a devastating disease without cure. The major cause of death among patients with pulmonary hypertension is right heart failure; however, biology of the right heart is not well understood. This lack of… read more here.
Keywords: redox; biology; hypertension; redox signaling ... See more keywords
Subcellular Redox Signaling.
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DOI: 10.1007/978-3-319-63245-2_25
Abstract: Oxidative and antioxidative system of cells and tissues maintains a balanced state under physiological conditions. A disruption in this balance of redox status has been associated with numerous pathological processes. Reactive oxygen species (ROS) as… read more here.
Keywords: subcellular redox; redox; biology; redox signaling ... See more keywords
Fatiguing Contractions Induce Acute Redox Signaling in Mouse Muscle
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.10.301
Abstract: Protein S-glutathionylation (P-SSG) is a reversible redox modification known to alter the activity of transcription factors, kinases, and contractile proteins as well as protect critical cysteine residues from irreversible oxidation. Exercise elicits an acute oxidative… read more here.
Keywords: mouse muscle; muscle; redox; fatiguing contractions ... See more keywords
Cysteine perthiosulfenic acid (Cys-SSOH): A novel intermediate in thiol-based redox signaling?☆
Sign Up to like & getrecommendations! Published in 2018 at "Redox Biology"
DOI: 10.1016/j.redox.2017.10.006
Abstract: The reversible oxidation of protein cysteine residues (Cys-SH) is a key reaction in cellular redox signaling involving initial formation of sulfenic acids (Cys-SOH), which are commonly detected using selective dimedone-based probes. Here, we report that… read more here.
Keywords: cys ssoh; cys; cys ssh; perthiosulfenic acid ... See more keywords
Teaching the basics of reactive oxygen species and their relevance to cancer biology: Mitochondrial reactive oxygen species detection, redox signaling, and targeted therapies
Sign Up to like & getrecommendations! Published in 2018 at "Redox Biology"
DOI: 10.1016/j.redox.2017.12.012
Abstract: Reactive oxygen species (ROS) have been implicated in tumorigenesis (tumor initiation, tumor progression, and metastasis). Of the many cellular sources of ROS generation, the mitochondria and the NADPH oxidase family of enzymes are possibly the… read more here.
Keywords: reactive oxygen; oxygen species; biology; redox signaling ... See more keywords
Interactions of zinc- and redox-signaling pathways
Sign Up to like & getrecommendations! Published in 2021 at "Redox Biology"
DOI: 10.1016/j.redox.2021.101916
Abstract: Zinc and cellular oxidants such as reactive oxygen species (ROS) each participate in a multitude of physiological functions. There is considerable overlap between the affected events, including signal transduction. While there is no obvious direct… read more here.
Keywords: oxidation; zinc; zinc ros; zinc redox ... See more keywords
The Role of BRG1 in Antioxidant and Redox Signaling
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DOI: 10.1155/2020/6095673
Abstract: Redox homeostasis is regulated by critical molecules that modulate antioxidant and redox signaling (ARS) within the cell. Imbalances among these molecules can lead to oxidative stress and damage to cell functions, causing a variety of… read more here.
Keywords: brg1; antioxidant redox; role brg1; role ... See more keywords
Redox signaling and Alzheimer’s disease: from pathomechanism insights to biomarker discovery and therapy strategy
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DOI: 10.1186/s40364-020-00218-z
Abstract: Abstract Aging and average life expectancy have been increasing at a rapid rate, while there is an exponential risk to suffer from brain-related frailties and neurodegenerative diseases as the population ages. Alzheimer’s disease (AD) is… read more here.
Keywords: pathomechanism insights; alzheimer disease; biomarker; disease ... See more keywords
Geniposide Balances the Redox Signaling to Mediate Glucose-Stimulated Insulin Secretion in Pancreatic β-Cells
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DOI: 10.2147/dmso.s240794
Abstract: Purpose To investigate the effect of geniposide on the biosynthesis of insulin and the expression protein disulfide isomerase (PDI) and endoplasmic reticulum oxidoreductin 1 (ERO1) in the presence of low (5 mM) and high (25… read more here.
Keywords: pancreatic cells; redox signaling; glucose stimulated; glucose ... See more keywords
Peroxisome-Derived Hydrogen Peroxide Modulates the Sulfenylation Profiles of Key Redox Signaling Proteins in Flp-In T-REx 293 Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.888873
Abstract: The involvement of peroxisomes in cellular hydrogen peroxide (H2O2) metabolism has been a central theme since their first biochemical characterization by Christian de Duve in 1965. While the role of H2O2 substantially changed from an… read more here.
Keywords: hydrogen peroxide; derived h2o2; peroxisome derived; h2o2 ... See more keywords
Role of Mitochondria in the Redox Signaling Network and Its Outcomes in High Impact Inflammatory Syndromes
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2020.568305
Abstract: Inflammation is associated with the release of soluble mediators that drive cellular activation and migration of inflammatory leukocytes to the site of injury, together with endothelial expression of adhesion molecules, and increased vascular permeability. It… read more here.
Keywords: signaling network; response; inflammation; inflammatory ... See more keywords