An Integrative Gene Expression and Mathematical Flux Balance Analysis Identifies Targetable Redox Vulnerabilities in Melanoma Cells
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DOI: 10.1158/0008-5472.can-19-3588
Abstract: An integrative bioinformatics, flux balance analysis, and experimental approach identify targetable redox vulnerabilities and show the potential for modulation of cancer antioxidant defense to augment the benefits of existing therapies in melanoma. Melanomas harboring BRAF… read more here.
Keywords: redox vulnerabilities; balance analysis; flux balance; targetable redox ... See more keywords