Dihydroceramide Desaturase 1 Inhibitors Reduce Amyloid-β Levels in Primary Neurons from an Alzheimer’s Disease Transgenic Model
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DOI: 10.1007/s11095-017-2312-2
Abstract: ABSTRACTPurposeThe induction of autophagy has recently been explored as a promising therapeutic strategy to combat Alzheimer’s disease. Among many other factors, there is evidence that ceramides/dihydroceramides act as mediators of autophagy, although the exact mechanisms… read more here.
Keywords: desaturase inhibitors; desaturase; alzheimer disease; reduce amyloid ... See more keywords