Is it possible to reduce glial activation in an old taupathia mouse model by deletion of microglial Hemoxygenase‐1?
Sign Up to like & getrecommendations! Published in 2024 at "Acta Ophthalmologica"
DOI: 10.1111/aos.16348
Abstract: Tauopathies such as Alzheimer's disease are characterized by the accumulation of neurotoxic aggregates of tau protein. With aging and, especially, in Alzheimer's patients, the inducible enzyme heme oxygenase 1 (HO‐1) progressively increases in microglia, causing… read more here.
Keywords: mice; possible reduce; glial activation; reduce glial ... See more keywords