A systems biology approach identifies candidate drugs to reduce mortality in severely ill patients with COVID-19
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abm2510
Abstract: Despite the availability of highly efficacious vaccines, coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lacks effective drug treatment, which results in a high rate of mortality. To address this… read more here.
Keywords: ill patients; biology approach; systems biology; reduce mortality ... See more keywords
Late-life physical activity changes after a cardiovascular event: can we reduce mortality risks?
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DOI: 10.1136/heartjnl-2022-321174
Abstract: Cardiovascular diseases (CVD) are highly prevalent conditions that carry one of the highest morbidity and mortality burdens worldwide. Physical activity is a known protective factor for prevention of noncommunicable diseases such as CVD, and for… read more here.
Keywords: mortality risks; physical activity; risk; activity ... See more keywords
Andrographolide and 4-Phenylbutyric Acid Administration Increase the Expression of Antimicrobial Peptides Beta-Defensin-1 and Cathelicidin and Reduce Mortality in Murine Sepsis
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DOI: 10.3390/antibiotics11111629
Abstract: Antibiotic resistance is a global threat and requires the search for new treatment strategies. Natural antimicrobial peptides (AMPs) have pronounced antibacterial, antiviral, antifungal, and antitumor activity. AMPs’ clinical use is complicated by the high synthesis… read more here.
Keywords: mortality murine; antimicrobial peptides; beta defensin; expression ... See more keywords