Nrf2 deficiency causes hepatocyte dedifferentiation and reduced albumin production in an experimental extrahepatic cholestasis model
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DOI: 10.1371/journal.pone.0269383
Abstract: The transcription factor Nrf2 modulates the initiation and progression of a number of diseases including liver disorders. We evaluated whether Nrf2 mediates hepatic adaptive responses to cholestasis. Wild-type and Nrf2-null mice were subjected to bile… read more here.
Keywords: cholestasis; nrf2 deficiency; expression; albumin production ... See more keywords