Evaluating auto‐contouring accuracy in reduced CT dose images for radiopharmaceutical therapies: Denoising and evaluation of 177Lu DOTATATE therapy dataset
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Applied Clinical Medical Physics"
DOI: 10.1002/acm2.70066
Abstract: Abstract Purpose Reducing radiation dose attributed to computed tomography (CT) may compromise the accuracy of organ segmentation, an important step in 177Lu DOTATATE therapy that affects both activity and mass estimates. This study aimed to… read more here.
Keywords: reduced dose; dotatate therapy; 177lu dotatate; accuracy ... See more keywords
Effectiveness and Safety of Reduced‐Dose Prasugrel in an East Asian Population: PRASFIT‐ACS Emulation Using National Health Insurance Claims Data
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DOI: 10.1002/cpt.70017
Abstract: Prasugrel is recommended for acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI). However, East Asians exhibit a stronger antiplatelet response, raising concerns about bleeding risks with standard dosing. This retrospective cohort study evaluated… read more here.
Keywords: reduced dose; dose prasugrel; east asian; prasfit acs ... See more keywords
Multi-courses of blinatumomab combined with reduced dose chemotherapy has been successfully used in chemo-intolerant middle to high-risk pediatric B-ALL patients with invasive fungal disease
Sign Up to like & getrecommendations! Published in 2025 at "Annals of Hematology"
DOI: 10.1007/s00277-025-06432-9
Abstract: Invasive fungal disease (IFD) remains a challenging complication and a leading cause of death in the treatment of childhood acute leukemia (AL). Blinatumomab is a novel bispecific antibody targeting CD19, with excellent anti-tumor effects against… read more here.
Keywords: chemotherapy; invasive fungal; reduced dose; dose chemotherapy ... See more keywords
Intra-patient comparison of reduced-dose model-based iterative reconstruction with standard-dose adaptive statistical iterative reconstruction in the CT diagnosis and follow-up of urolithiasis
Sign Up to like & getrecommendations! Published in 2017 at "European Radiology"
DOI: 10.1007/s00330-017-4783-2
Abstract: AbstractObjectivesTo evaluate the accuracy of reduced-dose CT scans reconstructed using a new generation of model-based iterative reconstruction (MBIR) in the imaging of urinary tract stone disease, compared with a standard-dose CT using 30% adaptive statistical… read more here.
Keywords: reconstruction; model based; iterative reconstruction; reduced dose ... See more keywords
Deep learning reconstruction for detection of liver lesions at standard-dose and reduced-dose abdominal CT
Sign Up to like & getrecommendations! Published in 2025 at "European Radiology"
DOI: 10.1007/s00330-025-11596-z
Abstract: Deep learning reconstruction (DLR) has shown promising image denoising ability, but its radiation dose reduction potential remains unknown. The objective of this study was to investigate the diagnostic performance of DLR compared to iterative reconstruction… read more here.
Keywords: detection; dose; standard dose; liver lesions ... See more keywords
Is there an increased risk of spinal relapse in standard-risk medulloblastoma/primitive neuroectodermal tumor patients who receive only a reduced dose of craniospinal radiotherapy?
Sign Up to like & getrecommendations! Published in 2018 at "Child's Nervous System"
DOI: 10.1007/s00381-018-3842-6
Abstract: PurposeMedulloblastoma (MBL) is the most common pediatric brain malignancy. Postoperative radiotherapy to the entire craniospinal axis is the standard-of-care but has linked to long-term morbidity. In this study, we analyzed the implication of reduced dose… read more here.
Keywords: risk; reduced dose; radiotherapy; relapse ... See more keywords
Comparable Efficacy of Reduced Dose Radiation Therapy for the Treatment of Early Stage Gastric Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue
Sign Up to like & getrecommendations! Published in 2021 at "Advances in Radiation Oncology"
DOI: 10.1016/j.adro.2021.100714
Abstract: Purpose This study compares reduced ( read more here.
Keywords: lymphoma; dose radiation; reduced dose; response ... See more keywords
Optimization of acquisition parameters for reduced-dose thoracic CT: A phantom study.
Sign Up to like & getrecommendations! Published in 2020 at "Diagnostic and interventional imaging"
DOI: 10.1016/j.diii.2020.01.012
Abstract: PURPOSE The purpose of this study was to analyze the impact of different options for reduced-dose computed tomography (CT) on image noise and visibility of pulmonary structures in order to define the best choice of… read more here.
Keywords: pulmonary structures; phantom; reduced dose; tube ... See more keywords
Standard of care vs reduced-dose chemoradiation after induction chemotherapy in HPV+ oropharyngeal carcinoma patients: The Quarterback trial.
Sign Up to like & getrecommendations! Published in 2019 at "Oral oncology"
DOI: 10.1016/j.oraloncology.2019.06.021
Abstract: BACKGROUND Human Papillomavirus oropharyngeal carcinoma (HPVOPC) has better progression free (PFS) and overall survival (OS) than non-HPVOPC. Standard-dose chemoradiotherapy (sdCRT) results in significant acute toxicity and late morbidity. We hypothesized that after induction chemotherapy (IC),… read more here.
Keywords: induction chemotherapy; reduced dose; dose chemoradiation; hpv ... See more keywords
New Strategy of Acute Graft-vs-Host Disease: Investigation of a Reduced Dose of Antithymocyte Globulin in Haploidentical Hematopoietic Stem Cell Transplantation.
Sign Up to like & getrecommendations! Published in 2019 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2018.10.028
Abstract: Graft-vs-host disease (GVHD) is one of the biggest challenges in haploidentical hematopoietic stem cell transplantation. Antithymocyte globulins (ATGs) are widely used to overcome GVHD, but excessive immunosuppression increases the chances of relapse and infection following… read more here.
Keywords: stem cell; haploidentical hematopoietic; reduced dose; transplantation ... See more keywords
Clinical Study of Standard- vs Reduced-Dose Tacrolimus Combined With Generic Mycophenolate Mofetil in De Novo Kidney Transplantation: A Prospective Randomized Trial.
Sign Up to like & getrecommendations! Published in 2019 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2019.11.029
Abstract: BACKGROUND The lowering of calcineurin inhibitor exposure is possibly considered as the proper strategy to prevent calcineurin inhibitor-induced nephrotoxicity in kidney transplant. This clinical study was designed to compare the efficacy and tolerability of reduced-dose… read more here.
Keywords: reduced dose; dose tacrolimus; group; standard dose ... See more keywords