Reduced Insulin Signaling Targeted to Serotonergic Neurons but Not Other Neuronal Subtypes Extends Lifespan in Drosophila melanogaster
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DOI: 10.3389/fnagi.2022.893444
Abstract: Reduced Insulin/IGF-like signaling (IIS) plays an evolutionarily conserved role in improving longevity and some measures of health-span in model organisms. Recent studies, however, have found a disconnection between lifespan extension and behavioral health-span. We have… read more here.
Keywords: lifespan; senescence; reduced insulin; serotonergic neurons ... See more keywords