Recurrent Sublethal-Dose Selection for Reduced Susceptibility of Palmer Amaranth (Amaranthus palmeri) to Dicamba
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DOI: 10.1017/wsc.2016.27
Abstract: The management of glyphosate-resistant Palmer amaranth has been a challenge in southern United States cropping systems. Registration of dicamba-resistant crops will provide an alternative management option to control herbicide-resistant Palmer amaranth populations, particularly those having… read more here.
Keywords: dicamba; palmer; palmer amaranth; reduced susceptibility ... See more keywords
Influenza A variants with reduced susceptibility to baloxavir isolated from Japanese patients are fit and transmit through respiratory droplets
Sign Up to like & getrecommendations! Published in 2019 at "Nature Microbiology"
DOI: 10.1038/s41564-019-0609-0
Abstract: Here we report the isolation of the influenza A/H1N1 2009 pandemic (A/H1N1pdm) and A/H3N2 viruses carrying an I38T mutation in the polymerase acidic protein—a mutation that confers reduced susceptibility to baloxavir marboxil—from patients before and… read more here.
Keywords: respiratory droplets; japanese patients; isolated japanese; susceptibility baloxavir ... See more keywords
Loss of ezrin expression reduced the susceptibility to the glomerular injury in mice
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-22846-0
Abstract: Ezrin is highly expressed in glomerular podocytes and is reported to form a multi-protein complex with scaffold protein Na+/H+ exchanger regulatory factor 2 (NHERF2) and podocalyxin, a major sialoprotein. Podocalyxin-knockout mice died within 24 h of… read more here.
Keywords: susceptibility glomerular; ezrin; mice; reduced susceptibility ... See more keywords
Induction of Antimicrobial Resistance of Stenotrophomonas maltophilia by Exposure to Nonlethal Levels of Antibiotics.
Sign Up to like & getrecommendations! Published in 2023 at "Microbial drug resistance"
DOI: 10.1089/mdr.2022.0202
Abstract: The effects of the sequential subculture in the presence of a driving force on antimicrobial resistance of Stenotrophomonas maltophilia K279a were investigated. Stationary-phase cells were inoculated into the lysogeny broth medium, with and without antibiotic… read more here.
Keywords: resistance stenotrophomonas; stenotrophomonas maltophilia; reduced susceptibility; resistance ... See more keywords
Listeria monocytogenes from food and food industry environments with reduced susceptibility to benzalkonium chloride, sodium hypochlorite and peracetic acid.
Sign Up to like & getrecommendations! Published in 2023 at "FEMS microbiology letters"
DOI: 10.1093/femsle/fnad019
Abstract: The growing number of Listeria monocytogenes strains displaying increased tolerance to sanitizers widely applied in the food industry is becoming a problem. The aims of this study were to evaluate the susceptibility of L. monocytogenes… read more here.
Keywords: food industry; food food; food; susceptibility ... See more keywords
Emerging resistance in Staphylococcus epidermidis during dalbavancin exposure: a case report and in vitro analysis of isolates from prosthetic joint infections
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkac434
Abstract: Abstract Background Dalbavancin, a semisynthetic lipoglycopeptide with exceptionally long half-life and Gram-positive spectrum, is an attractive option for infections requiring prolonged therapy, including prosthetic joint infections (PJIs). Objectives To investigate the prevalence of reduced susceptibility… read more here.
Keywords: prosthetic joint; dalbavancin; reduced susceptibility; resistance ... See more keywords
Evaluation of Resistance Development to the Gwt1 Inhibitor Manogepix (APX001A) in Candida Species
Sign Up to like & getrecommendations! Published in 2019 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01387-19
Abstract: Manogepix (MGX) targets the conserved fungal Gwt1 enzyme required for acylation of inositol early in the glycosylphosphatidylinositol biosynthesis pathway. The prodrug fosmanogepix is currently in clinical development for the treatment of invasive fungal infections. ABSTRACT… read more here.
Keywords: reduced susceptibility; gwt1; development; resistance ... See more keywords
Antimicrobial Susceptibility Survey of Invasive Haemophilus influenzae in the United States in 2016
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DOI: 10.1128/spectrum.02579-21
Abstract: Antibiotics play an important role for the treatment and prevention of invasive Haemophilus influenzae disease. Antimicrobial resistance survey of invasive H. influenzae isolates collected in 2016 showed that the US H. influenzae population remained susceptible… read more here.
Keywords: influenzae; invasive haemophilus; haemophilus influenzae; susceptibility ... See more keywords
Influenza A(H3N2) virus exhibiting reduced susceptibility to baloxavir due to a polymerase acidic subunit I38T substitution detected from a hospitalised child without prior baloxavir treatment, Japan, January 2019
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DOI: 10.2807/1560-7917.es.2019.24.12.1900170
Abstract: In January 2019, two influenza A(H3N2) viruses carrying an I38T substitution in the polymerase acidic subunit (PA), which confers reduced susceptibility to baloxavir, were detected from epidemiologically unrelated hospitalised children in Japan. The viruses exhibited… read more here.
Keywords: reduced susceptibility; h3n2; january 2019; baloxavir ... See more keywords
Time Is of the Essence—Early Activation of the Mevalonate Pathway in Apple Challenged With Gray Mold Correlates With Reduced Susceptibility During Postharvest Storage
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.797234
Abstract: Apple is typically stored under low temperature and controlled atmospheric conditions to ensure a year round supply of high quality fruit for the consumer. During storage, losses in quality and quantity occur due to spoilage… read more here.
Keywords: mevalonate pathway; apple; reduced susceptibility; activation mevalonate ... See more keywords
Recent Evolution of Susceptibility to Beta-Lactams in Neisseria meningitidis
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DOI: 10.3390/antibiotics12060992
Abstract: Beta-lactams are the main antibiotics for the treatment of invasive meningococcal disease. However, reduced susceptibility to penicillin G is increasingly reported in Neisseria meningitidis and reduced susceptibility to third-generation cephalosporines (3GC) and the rare acquisition… read more here.
Keywords: neisseria meningitidis; beta; susceptibility penicillin; susceptibility ... See more keywords