A small molecule that disrupts S. Typhimurium membrane voltage without cell lysis reduces bacterial colonization of mice
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DOI: 10.1371/journal.ppat.1010606
Abstract: As pathogenic bacteria become increasingly resistant to antibiotics, antimicrobials with mechanisms of action distinct from current clinical antibiotics are needed. Gram-negative bacteria pose a particular problem because they defend themselves against chemicals with a minimally… read more here.
Keywords: small molecule; reduces bacterial; outer membrane; bacterial colonization ... See more keywords