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Experimental and Theoretical Investigation of MALDI In-Source Decay of Peptides with a Reducing Matrix: What Is the Initial Fragmentation Step?

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Published in 2022 at "Journal of the American Society for Mass Spectrometry"

DOI: 10.1021/jasms.2c00066

Abstract: Matrix-assisted laser desorption/ionization in-source decay (MALDI-ISD) with a reducing matrix is believed to be initiated by hydrogen transfer from the matrix to the peptide. Several new matrices have recently been developed to achieve more efficient… read more here.

Keywords: fragmentation; source decay; reducing matrix; maldi isd ... See more keywords