Potent inhibition of human carbonyl reductase 1 (CBR1) by the prenylated chalconoid xanthohumol and its related prenylflavonoids isoxanthohumol and 8-prenylnaringenin.
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DOI: 10.1016/j.cbi.2019.02.031
Abstract: In terms of drug disposal and metabolism SDR21C1 (carbonyl reductase 1; CBR1) exerts an assorted substrate spectrum among a large variety of clinically relevant substances. Additionally, this short-chain dehydrogenase/reductase is extensively expressed in most tissues… read more here.
Keywords: reductase; reductase cbr1; isoxanthohumol prenylnaringenin; carbonyl reductase ... See more keywords