Thioredoxin reductase 1 knockdown disrupts pigment synthesis in melanocytes
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DOI: 10.1016/j.freeradbiomed.2018.10.131
Abstract: Our labs have shown that levels of the antioxidant enzyme thioredoxin reductase 1 (TR1) is increased in human malignant melanomas relative to benign nevi (moles), and that TR1 knockdown affects mitochondrial metabolism in human melanomas.… read more here.
Keywords: thioredoxin reductase; reductase knockdown; tr1; knockdown disrupts ... See more keywords