Synthesis of Chromeno[3,4-b]piperazines by an Enol-Ugi/Reduction/Cyclization Sequence
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DOI: 10.3390/molecules26051287
Abstract: Keto piperazines and aminocoumarins are privileged building blocks for the construction of geometrically constrained peptides and therefore valuable structures in drug discovery. Combining these two heterocycles provides unique rigid polycyclic peptidomimetics with drug-like properties including… read more here.
Keywords: chromeno piperazines; reduction cyclization; enol ugi; ugi reduction ... See more keywords