A pH/reduction dual-sensitive copolymer inserted in liposomal bilayer acts as a protective “umbrella”
Sign Up to like & getrecommendations! Published in 2020 at "Colloids and Surfaces A: Physicochemical and Engineering Aspects"
DOI: 10.1016/j.colsurfa.2020.125128
Abstract: Abstract Developing a targeted intelligent drug delivery system with excellent controllability of drug release remains an ongoing challenge in chemotherapy. A multistage responsive liposome was constructed by inserting a folate (FA) modified lipid and a… read more here.
Keywords: drug; dual sensitive; bilayer; liposomal bilayer ... See more keywords
Core cross-linked poly(ethylene glycol)-graft-Dextran nanoparticles for reduction and pH dual responsive intracellular drug delivery.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2017.02.032
Abstract: A kind of core cross-linked poly(ethylene glycol)-graft-Dextran nanoparticles (CPD NPs) was prepared by a simple chemical cross-linking method for reduction and pH dual response drug delivery. The resultant CPD NPs are of homogeneous spherical structure… read more here.
Keywords: drug delivery; cross; reduction dual; cpd nps ... See more keywords
Construction of Ginsenosides nanoparticles with pH/reduction dual response for enhancement of its cytotoxicity towards HepG2 cells.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.0c03698
Abstract: The aim of this study is to construct a pH and reduction responsive nanodrug delivery system to effectively deliver ginsenoside (Rh2) and enhance its cytotoxicity against human hepatocarcinoma cells (HepG2). Here, pullulan polysaccharide was grafted… read more here.
Keywords: rh2 nps; rh2; dual response; cytotoxicity ... See more keywords
A pH and reduction dual-sensitive polymeric nanomicelle for tumor microenvironment triggered cellular uptake and controlled intracellular drug release.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials science"
DOI: 10.1039/c9bm00825j
Abstract: Minimal drug leakage during blood circulation and intracellular drug delivery in tumor sites are of great significance in chemotherapeutics. Herein we propose an interlayer crosslinked polymeric micelle with tumor acidity and reduction dual sensitivity for… read more here.
Keywords: drug; dual sensitive; reduction dual; intracellular drug ... See more keywords
Construction of pH/reduction dual responsive MSN-HAgel containing HApt for tumor targeting carriers
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d2ra02290g
Abstract: In this study, a pH/reduction dual responsive carrier containing 42nt-nucleic acid HApt based on mesoporous silica nanoparticles (MSNs) was designed. Two kinds of low molecular weight oligomeric hyaluronic acid (HA) were used to graft onto… read more here.
Keywords: msn; msn hagel; hapt; dual responsive ... See more keywords