Reduction of lamin B receptor levels by miR-340-5p disrupts chromatin, promotes cell senescence and enhances senolysis.
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DOI: 10.1093/nar/gkab538
Abstract: A major stress response influenced by microRNAs (miRNAs) is senescence, a state of indefinite growth arrest triggered by sublethal cell damage. Here, through bioinformatic analysis and experimental validation, we identified miR-340-5p as a novel miRNA… read more here.
Keywords: lamin receptor; reduction lamin; senescence; senescent ... See more keywords