A safe and selective method for reduction of 2-nitrophenylacetic acid systems to N-aryl hydroxamic acids using continuous flow hydrogenation
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DOI: 10.1016/j.tetlet.2017.01.008
Abstract: Abstract The cyclic hydroxamic acid functional group is critical to the biological activity of numerous natural products and drug candidates. Efficient, reliable, and green synthetic methods to produce cyclic hydroxamic acids are needed. Herein, flow… read more here.
Keywords: hydroxamic acids; flow hydrogenation; reduction nitrophenylacetic; nitrophenylacetic acid ... See more keywords