Enantioselective reductive allylic alkylation enabled by dual photoredox/palladium catalysis.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d2cc06705f
Abstract: A dual photoredox/palladium catalyzed regio- and enantioselective reductive cross-coupling of allylic acetates with tertiary/secondary alkyl bromides has been achieved, and Hantzsch ester is used as a homogeneous organic reductant. This straightforward protocol enables the stereoselective… read more here.
Keywords: reductive allylic; photoredox palladium; dual photoredox; enantioselective reductive ... See more keywords
Ligand-Free Nickel-Catalyzed Reductive Allylic Defluorinative Cross-Coupling of α-Trifluoromethyl Alkenes with Epoxides
Sign Up to like & getrecommendations! Published in 2020 at "Synlett"
DOI: 10.1055/s-0040-1707170
Abstract: We report a reductive allylic defluorinative reaction of α-trifluoromethyl alkenes with terminal epoxides, which consists of an iodide-mediated regioselective ring opening and a nickel-catalyzed radical-type cross-coupling, providing diverse tertiary gem-difluorobishomoallylic alcohols in moderate to high… read more here.
Keywords: trifluoromethyl alkenes; allylic defluorinative; reductive allylic; nickel catalyzed ... See more keywords